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Association between betel-nut chewing and chronic kidney disease in men

Bibliographic Data

ID15092524
AuthorsChe-Yi Chou (0000-0002-3400-171X), Che‐yi Chou (0000-0003-4029-9097, China Medical University Hospital), Shi-Yann Cheng, Shi‐Yann Cheng (China Medical University), Jiung-Hsiun Liu (0000-0002-7241-9359, China Medical University Hospital), Wen-Chun Cheng (China Medical University, corresponding author), I-Min Kang (China Medical University Beigang Hospital), Yu-Hsiang Tseng, Yu‐Hsiang Tseng (China Medical University), Chuen-Ming Shih, Chuen‐Ming Shih (China Medical University Beigang Hospital), Walter Chen (0000-0001-6926-0837, China Medical University)
Year2009
Volume12
Issue5
Pages723-727
Publication date2009-05-01
Open AccessYes
TypeARTICLE
VenuePublic Health Nutrition (JOURNAL)
Journal identifiersISSN: 1368-9800 • E-ISSN: 1475-2727
PublisherCambridge University Press (CUP) (PUBLISHER)
DOI10.1017/s1368980008003339
PMID18647430
OpenAlexW2161169623
LanguageEN
Citations received3
References cited19

Background Betel-nut use is associated with metabolic syndrome and obesity. However, the association between betel-nut chewing and risk for chronic kidney disease (CKD) is unknown. The present study was conducted to determine the association between betel-nut chewing and CKD in men. Methods We retrospectively reviewed health-check records of 3264 men in a hospital-based cross-sectional screening programme from 2003 to 2006. CKD was defined as estimated glomerular filtration rate less than 60 ml/min/1·73 m 2 calculated by the Modification of Diet in Renal Disease formula. Risk factors for CKD including diabetes, hypertension, BMI, smoking, alcohol consumption and age were also considered. Results A total of 677 (20·7 %) men were found to have CKD and 427 (13·1 %) participants reported a history of betel-nut use. The prevalence (24·8 %) of CKD in betel-nut users was significantly higher than that (11·3 %) of participants without betel-nut use ( P = 0·026). In multivariate logistic regression analysis with adjustments for age, hypertension, diabetes and hyperlipidaemia, betel-nut use was independently associated with CKD ( P Conclusions Betel-nut use is associated with CKD in men. The association between betel-nut use and CKD is independent of age, BMI, smoking, alcohol consumption, hypertension, diabetes and hyperlipidaemia

Betel · Diabetes mellitus · Kidney disease · Logistic regression · Metabolic syndrome · Nut · Obesity · Odds ratio · Renal function · Traditional medicine · Head and Neck Cancer Studies · Medicine · Oral and gingival health research · Oral Health Pathology and Treatment · Endocrinology · Internal Medicine

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Citations per year0.33
Citation span2017 - 2023 (7)
Highly citedNo

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