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Global patterns in vision loss burden due to vitamin A deficiency from 1990 to 2017

Bibliographic Data

ID15093199
AuthorsYufeng Xu (0000-0002-9070-5586, Second Affiliated Hospital of Zhejiang University), Yi Shan (0000-0001-5852-1122, Second Affiliated Hospital of Zhejiang University), Xiling Lin (Second Affiliated Hospital of Zhejiang University), Qi Miao (0000-0003-4250-2239, Second Affiliated Hospital of Zhejiang University), Lixia Lou (0000-0001-9411-7776, Second Affiliated Hospital of Zhejiang University), Yijie Wang (0000-0001-6927-6505, Second Affiliated Hospital of Zhejiang University), Juan Ye (0000-0002-1948-2500, Second Affiliated Hospital of Zhejiang University, corresponding author)
Year2021
Volume24
Issue17
Pages5786-5794
Publication date2021-12-01
Open AccessYes
TypeARTICLE
VenuePublic Health Nutrition (JOURNAL)
Journal identifiersISSN: 1368-9800 • E-ISSN: 1475-2727
PublisherCambridge University Press (CUP) (PUBLISHER)
DOI10.1017/s1368980021001324
PMID33775269
OpenAlexW3151910525
LanguageEN
Citations received4
References cited42

Objective: To investigate the vision loss burden due to vitamin A deficiency (VAD) at the global, regional and national levels by year, age, sex and socio-economic status using prevalence and years lived with disability (YLD). Design: International, retrospective, comparative burden-of-disease study. Setting: Prevalence and YLD data were extracted from the Global Burden of Disease (GBD) Study 2017. The association of age-standardised YLD rates and human development index (HDI) was tested by Pearson correlation and linear regression analyses. The Gini coefficient and concentration index (CI) were calculated to demonstrate the trends in between-country inequality in vision loss burden due to VAD. Participants: All participants met the GBD inclusion criteria. Results: The age-standardised prevalence rate increased by 9·2 %, while the age-standardised YLD rates rose by 10·8 % from 1990 to 2017. Notably, the vision loss burden caused by VAD showed a declining trend since 2014. The vision loss burden was more concentrated in the post-neonatal age group and decreased with increasing age. The age-standardised YLD rates were inversely correlated with HDI ( r = –0·2417, P = 0·0084). The CI and Gini coefficients indicated that socio-economic-related and between-country inequality declined from 2000 to 2017. VAD was the eighth leading cause of the age-standardised prevalence rate and ninth leading cause of age-standardised YLD rate among fifteen causes of vision loss in 2017. Conclusion: VAD has become one of the significant leading causes of vision loss globally. Efforts to control vision impairment related to VAD are needed, especially for children in countries with lower socio-economic status

Burden of disease · Disease burden · Economic inequality · Environmental health · Gini coefficient · Inequality · Population · Vitamin D and neurology · vitamin D deficiency · Antioxidant Activity and Oxidative Stress · Demography · Medicine · Ophthalmology and Visual Impairment Studies · Retinal Diseases and Treatments · Internal Medicine · Pediatrics

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Citations per year1
Citation span2022 - 2025 (4)
Highly citedNo

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