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Macronutrient intake and type 2 diabetes risk in middle-aged Australian women. Results from the Australian Longitudinal Study on Women's Health

Bibliographic Data

ID15093809
AuthorsAmani Alhazmi (0000-0002-4062-1640, University of Newcastle Australia), Elizabeth Stojanovski (0000-0002-2507-3877, University of Newcastle Australia), Mark Mcevoy (0000-0002-0930-8605, University of Newcastle Australia), Manohar L Garg (0000-0003-0514-0865, University of Newcastle Australia, corresponding author)
Year2014
Volume17
Issue7
Pages1587-1594
Publication date2014-07-01
Open AccessYes
TypeARTICLE
VenuePublic Health Nutrition (JOURNAL)
Journal identifiersISSN: 1368-9800 • E-ISSN: 1475-2727
PublisherCambridge University Press (CUP) (PUBLISHER)
DOI10.1017/s1368980013001870
PMID23866795
OpenAlexW2125851136
LanguageEN
References cited45

Objective To investigate the association between macronutrient intake and type 2 diabetes risk in middle-aged Australian women. Design A prospective cohort study, with 6 years (2002–2007) of follow up. Dietary intake was assessed with a validated FFQ. Relative risks with 95 % confidence intervals were used to examine risk associations. Setting Australian Longitudinal Study on Women's Health, Australia. Subjects Australian women ( n 8370) from the Australian Longitudinal Study on Women's Health aged 45–50 years and free of type 2 diabetes at baseline. Results After 6 years of follow-up, 311 women developed type 2 diabetes. After adjusting for sociodemographic, lifestyle and other dietary risk factors, MUFA, total n -3 PUFA, α-linolenic acid and total n -6 PUFA intakes were positively associated with the incidence of type 2 diabetes. The relative risks for type 2 diabetes for the highest compared with the lowest quintiles were 1·64 (95 % CI 1·06, 2·54), P = 0·04 for MUFA; 1·55 (95 % CI 1·03, 2·32), P = 0·01 for n -3 PUFA; 1·84 (95 % CI 1·25, 2·71), P P = 0·04 for n -6 PUFA. Other dietary macronutrients were not significantly associated with diabetes risk. Conclusions The data indicate that consumption of MUFA, n -3 PUFA and n -6 PUFA may influence the risk of developing type 2 diabetes in women

Biology · Cohort study · Confidence interval · Diabetes mellitus · Environmental health · Fatty acid · Incidence (geometry · Longitudinal study · Lower risk · Polyunsaturated fatty acid · Prospective cohort study · Relative risk · Type 2 diabetes · Demography · Fatty Acid Research and Health · Medicine · Nutritional Studies and Diet · Obesity, Physical Activity, Diet · Endocrinology · Gerontology · Internal Medicine

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Highly citedNo

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