Associations of the pre-pregnancy weight status with anaemia and the erythropoiesis-related micronutrient status

Bibliographic Data

ID15095027
AuthorsNoor Rohmah Mayasari (0000-0003-3742-7705), Tzu-Yu Hu, Jane C-J Chao (0000-0002-3610-9580), Chyi-Huey Bai (0000-0002-9016-4919, Taipei Medical University), Yi-Chun Chen (0000-0002-3682-6168), Yi Chun Chen (0000-0001-6031-8414), Ya Li Huang (Taipei Medical University), Chun-Chao Chang (Taipei Medical University Hospital), Fan-Fen Wang (Taipei City Hospital), Hamam Hadi (0000-0002-1945-2539), Esti Nurwanti (Universitas Pembangunan Nasional Veteran Jakarta), Jung-Su Chang (0000-0001-8608-9349, Taipei Medical University Hospital, corresponding author)
Year2021
Volume24
Issue18
Pages6247-6257
Publication date2021-12-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenuePublic Health Nutrition (JOURNAL)
Journal identifiersISSN: 1368-9800 • E-ISSN: 1475-2727
PublisherCambridge University Press (CUP) (PUBLISHER)
DOI10.1017/s1368980021002627
PMID34120669
OpenAlexW3168395355
LanguageEN
Citations received2
References cited33

Objective: The coexistence of underweight (UW) and overweight (OW)/obese (OB) at the population level is known to affect iron deficiency (ID) anaemia (IDA), but how the weight status affects erythropoiesis during pregnancy is less clear at a population scale. This study investigated associations between the pre-pregnancy BMI (pBMI) and erythropoiesis-related nutritional deficiencies. Design: Anthropometry, blood biochemistry and 24-h dietary recall data were collected during prenatal care visits. The weight status was defined based on the pBMI. Mild nutrition deficiency-related erythropoiesis was defined if individuals had an ID, folate depletion or a vitamin B 12 deficiency. Setting: The Nationwide Nutrition and Health Survey in Taiwan (Pregnant NAHSIT 2017–2019). Participants: We included 1456 women aged 20 to 45 years with singleton pregnancies. Results: Among these pregnant women, 9·6 % were UW, and 29·2 % were either OW (15·8 %) or OB (13·4 %). A U-shaped association between the pBMI and IDA was observed, with decreased odds (OR; 95 % CI) for OW subjects (0·6; 95 % CI (0·4, 0·9)) but increased odds for UW (1·2; 95 % CI (0·8, 2·0)) and OB subjects (1·2; 95 % CI (0·8, 1·8)). The pBMI was positively correlated with the prevalence of a mild nutritional deficiency. Compared to normal weight, OB pregnant women had 3·4-fold (3·4; 95 % CI (1·4, 8·1)) higher odds for multiple mild nutritional deficiencies, while UW individuals had lowest odds (0·3; 95 % CI (0·1, 1·2)). A dietary analysis showed negative relationships of pBMI with energy, carbohydrates, protein, Fe and folate intakes, but positive relationship with fat intakes. Conclusion: The pre-pregnancy weight status can possibly serve as a good nutritional screening tool for preventing IDA during pregnancy

Body weight · Iron status · Micronutrient · Micronutrient deficiency · Nutrition Disorders · Weight loss · Folate and B Vitamins Research · Gestational Diabetes Research and Management · Iron Metabolism and Disorders

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