Does coffee, tea and caffeine consumption reduce the risk of incident breast cancer? A systematic review and network meta-analysis
Bibliographic Data
| ID | 15095580 |
|---|---|
| Authors | Shu Wang (0009-0009-1730-2316), Xiang Li (0000-0001-6509-2709), Yue Yang (0009-0009-2926-3596), Jingping Xie, Mingyue Liu (0000-0001-9563-1486), Ya Zhang (0000-0002-9717-911X), Yingshi Zhang (0000-0003-3101-6497), Qingchun Zhao (0000-0001-9256-9971) |
| Year | 2021 |
| Volume | 24 |
| Issue | 18 |
| Pages | 6377-6389 |
| Publication date | 2021-12-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Public Health Nutrition (JOURNAL) |
| Journal identifiers | ISSN: 1368-9800 • E-ISSN: 1475-2727 |
| Publisher | Cambridge University Press (CUP) (PUBLISHER) |
| DOI | 10.1017/s1368980021000720 |
| Language | EN |
| References cited | 72 |
Objective: We aimed to evaluate the association between coffee and/or tea consumption and breast cancer (BC) risk among premenopausal and postmenopausal women and to conduct a network meta-analysis. Design: Systematic review and network meta-analysis. Setting: We conducted a systematic review of electronic publications in the last 30 years to identify case–control studies or prospective cohort studies that evaluated the effects of coffee and tea intake. Results: Forty-five studies that included more than 3 323 288 participants were eligible for analysis. Network meta-analysis was performed to determine the effects of coffee and/or tea consumption on reducing BC risk in a dose-dependent manner and differences in coffee/tea type, menopause status, hormone receptor and the BMI in subgroup and meta-regression analyses. According to the first pairwise meta-analysis, low-dose coffee intake and high-dose tea intake may exhibit efficacy in preventing ER(estrogen receptor)− BC, particularly in postmenopausal women. Then, we performed another pairwise and network meta-analysis and determined that the recommended daily doses were 2–3 cups/d of coffee or ≥5 cups/d of tea, which contained a high concentration of caffeine, particularly in postmenopausal women. Conclusions: Coffee and tea consumption is not associated with a reduction in the overall BC risk in postmenopausal women and is associated with a potentially lower risk of ER− BC. And the highest recommended dose is 2–3 cups of coffee/d or ≥5 cups of tea/d. They are potentially useful dietary protectants for preventing BC
| Highly cited | No |
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