Leveraging Implementation Science to Address Health Disparities in Genomic Medicine
Examples from the Field
Bibliographic Data
| ID | 15314883 |
|---|---|
| Authors | Megan C Roberts (0000-0003-3434-2773, University of North Carolina at Chapel Hill, corresponding author), George A Mensah (0000-0002-0387-5326, National Institutes of Health), Muin J Khoury (0000-0002-9887-443X, Office of Public Health Genomics) |
| Year | 2019 |
| Volume | 29 |
| Issue | Suppl 1 |
| Pages | 187-192 |
| Publication date | 2019-02-21 |
| Peer Reviewed | Yes |
| Open Access | No |
| Type | ARTICLE |
| Venue | Ethnicity & Disease (JOURNAL) |
| Journal identifiers | ISSN: 1049-510X • E-ISSN: 1945-0826 |
| Publisher | Ethnicity & Disease, Inc (PUBLISHER) |
| DOI | 10.18865/ed.29.s1.187 |
| PMID | 30906168 |
| OpenAlex | W2917004747 |
| Language | EN |
| Citations received | 3 |
| References cited | 7 |
The integration of genomic data into screening, prevention, diagnosis, and treatment for clinical and public health practices has been slow and challenging. Implementation science can be applied in tackling the barriers and challenges as well as exploring opportunities and best practices for integrating genomic data into routine clinical and public health practice.In this article, we define the state of disparities in genomic medicine and focus predominantly on late-stage research findings. We use case studies from genetic testing for cardiovascular diseases (familial hypercholesterolemia) and cancer (Lynch syndrome and hereditary breast and ovarian cancer syndrome) in high-risk populations to consider current disparities and related barriers in turning genomic advances into population health impact to advance health equity. Finally, we address how implementation science can address these translational barriers and we discuss the strategic importance of collaborative multi-stakeholder approaches that engage public health agencies, professional societies, academic health and research centers, community clinics, and patients and their families to work collectively to improve population health and reduce or eliminate health inequities
Biology · Computational biology · Data science · Field (mathematics · Genomic medicine · Health equity · Pathology · Precision medicine · Public health · BRCA gene mutations in cancer · Computer Science · Health Policy Implementation Science · Health Systems, Economic Evaluations, Quality of Life · Medicine
Assessing Bias Toward a Black or White Simulated Patient with Obesity in a Virtual Reality-Based Genomics Encounter
Using social media listening to understand barriers to genomic medicine for those living with Ehlers–Danlos syndromes and hypermobility spectrum disorders
Extending an Antiracism Lens to the Implementation of Precision Public Health Interventions
Making sense of implementation theories, models and frameworks
A refined compilation of implementation strategies
Fostering implementation of health services research findings into practice
An introduction to implementation science for the non-specialist
Evaluating and improving the implementation of a community-based hereditary cancer screening program
Transdisciplinary Cardiovascular and Cancer Health Disparities Training
Harnessing Implementation Science to Increase the Impact of Health Equity Research
| Unique citing works | 3 |
|---|---|
| Citations per year | 1 |
| Citation span | 2023 - 2024 (2) |
| Citation velocity | recent |
| Highly cited | No |
| Citation types | Neutral: 3 |