Adherence and virologic suppression during the first 24 weeks on antiretroviral therapy among women in Johannesburg, South Africa - a prospective cohort study

Bibliographic Data

ID15365460
AuthorsZiad El‐Khatib (Karolinska Institutet), Ziad El-Khatib (0000-0003-0756-7280), Anna Mia Ekström (0000-0002-3912-1171, Karolinska Institutet), Ashraf Coovadia (0000-0002-6372-8846, University of the Witwatersrand), Elaine J Abrams (0000-0001-7938-8981, Columbia University), Max Petzold (0000-0003-4908-2169, Nordic School of Public Health, corresponding author), David Katzenstein (0000-0002-8593-4560, Stanford University), Lynn Morris (0000-0003-3961-7828, National Institute for Communicable Diseases), Louise Kuhn (0000-0002-2305-8665, Columbia University)
Year2011
Volume11
Issue1
Pages88-88
Publication date2011-02-08
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueBMC Public Health (JOURNAL)
Journal identifiersISSN: 1471-2458 • E-ISSN: 1471-2458
PublisherBioMed Central (PUBLISHER • GB)
DOI10.1186/1471-2458-11-88
PMID21303548
PMCIDPMC3046911
OpenAlexW2134462542
LanguageEN
Citations received9
References cited44

Virologic response to NNRTI-treatment in the cohort was excellent. However, women who received sdNVP were at greater risk of virologic failure when adherence was <95%. Women exposed to sdNVP, and those with less education and less social support may benefit from additional adherence counseling to ensure the long-term success of ART. More than 80% adherence may be sufficient to maintain virologic suppression on NNRTI-based regimens in the short-term, however complete adherence should be encouraged

Antiretroviral therapy · Cohort · Cohort study · Human immunodeficiency virus (HIV · Logistic regression · Nevirapine · Odds ratio · Pill · Prospective cohort study · Viral load · Viremia · HIV Research and Treatment · HIV/AIDS drug development and treatment · HIV/AIDS Research and Interventions · Medicine · Immunology · Internal Medicine · Pediatrics