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Examining the Roles of Psychological Inflexibility and Distress Tolerance on Cigarette Dependence and Binge Drinking among Individuals who Co-use Cannabis for Therapeutic Purposes

Bibliographic Data

ID15440467
AuthorsSilvana Agterberg (0000-0003-3613-5241, Montefiore Medical Center), Mary Barna Bridgeman (0000-0001-7947-9875, Rutgers, the State University of New Jersey), Benjamin Billingsley (0000-0002-6534-2867, The Concord Consortium), Rachel Rosen (0000-0003-3949-3060, Massachusetts General Hospital), Rachel L Rosen (0000-0003-4881-9595), Thomas W O’Kane (0000-0002-0161-8262, Rutgers, the State University of New Jersey), Marc L Steinberg (0000-0001-8180-8682, Johnson University, corresponding author)
Year2025
Publication date2025-11-21
Open AccessYes
TypeARTICLE
VenueInternational Journal of Mental Health and Addiction (JOURNAL)
Journal identifiersISSN: 1557-1874 • E-ISSN: 1557-1882
PublisherSpringer Science+Business Media (PUBLISHER • DE)
DOI10.1007/s11469-025-01594-z
OpenAlexW4416498193
LanguageEN
References cited37

The aims of this study were to examine associations between psychological inflexibility and (1) cigarette dependence among individuals who co-use cannabis and combustible cigarettes, and (2) binge drinking among individuals who co-use cannabis and alcohol. Adults attending a medical marijuana dispensary (N = 697) completed a survey examining cannabis use, cigarette smoking, binge drinking, psychological inflexibility, and distress tolerance. Psychological inflexibility was associated with greater cigarette dependence ( β = .325, p = .013) and binge drinking ( β = .303, p < .001). In linear but not zero-inflated negative binomial models, distress tolerance moderated the relationship between psychological inflexibility and binge drinking frequency ( β = .160, p = .003), though not the relationship between psychological inflexibility and cigarette dependence. Findings highlight the role of psychological inflexibility in the use of cigarettes and alcohol among people who co-use cannabis for therapeutic purposes. This population may benefit from interventions aimed at reducing psychological inflexibility and improving distress tolerance

Binge drinking · Cannabis · Dispensary · Distress · Health psychology · Polysubstance dependence · Population · Psychological distress · Psychological intervention · Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes · Resilience and Mental Health · Substance Abuse Treatment and Outcomes

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