Acceptance and Commitment Therapy-Based Smartphone Applications for Cessation of Tobacco Use among Adults with High Nicotine Dependence

Results from the iCanQuit Randomized Trial

Bibliographic Data

ID21645339
AuthorsMargarita Santiago-Torres (0000-0001-6051-3172, Fred Hutch Cancer Center, corresponding author), Kristin E Mull (0000-0002-7918-3078, Fred Hutch Cancer Center), Brianna M Sullivan (0000-0001-8290-780X, Fred Hutch Cancer Center), Nancy A Rigotti (0000-0002-2223-1657, Tobacco Research and Treatment Center, Division of General Internal Medicine, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA), Jonathan B Bricker (0000-0002-5694-8795, Fred Hutch Cancer Center)
Year2023
Volume58
Issue3
Pages354-364
Publication date2023-02-23
Open AccessNo
TypeARTICLE
VenueSubstance Use & Misuse (JOURNAL)
Journal identifiersISSN: 1082-6084 • E-ISSN: 1532-2491
PublisherInforma UK Limited (PUBLISHER • GB)
DOI10.1080/10826084.2022.2161317
PMID36683573
OpenAlexW4317732976
LanguageEN
Citations received1
References cited49

Background: With 1 in 2 adult tobacco users being highly dependent on nicotine, population-based interventions specifically designed for this group are urgently needed. This study used data from a randomized trial to evaluate whether (1) Acceptance and Commitment Therapy (ACT) delivered via a smartphone application (iCanQuit) would be more efficacious for cessation of nicotine-containing tobacco products than the US Clinical Practice Guidelines (USCPG)-based application (QuitGuide) among highly nicotine-dependent adults, (2) the effect of treatment on cessation was mediated by increases in acceptance of cravings to smoke, and (3) treatment utilization and satisfaction differed by arm. Methods: A total of 1452 highly nicotine-dependent adults received the iCanQuit or QuitGuide application for 12-months. Cessation outcomes were self-reported complete-case 30-day abstinence of nicotine-containing tobacco products (e.g., combustible cigarettes, e-cigarettes, chewing tobacco, snus, hookahs, cigars, cigarillos, tobacco pipes, and kreteks) at 3, 6, and 12-month post-randomization timepoints, missing-as-smoking, and multiple imputation analyses. Acceptance of cues to smoke and satisfaction with the applications was also reported. Results: Participants who received iCanQuit were significantly more likely to report 30-day abstinence of nicotine-containing tobacco products than those who received QuitGuide at 12-months (24% vs. 17%; OR = 1.47 95% CI: 1.11, 1.95). iCanQuit participants utilized their application more frequently and reported greater satisfaction than those who received QuitGuide. Increases in participants’ acceptance of cues to smoke mediated the intervention effect on cessation of nicotine-containing tobacco products. Conclusions: Among nicotine-dependent adults, an application-delivered ACT-based intervention was more engaging and efficacious than a USCPG-based intervention for cessation of nicotine-containing tobacco products

Abstinence · Environmental health · Nicotine · Nicotine replacement therapy · Nicotine withdrawal · Population · Psychiatry · Psychological intervention · Randomized controlled trial · Smoke · Smoking cessation · Behavioral Health and Interventions · Media Influence and Health · Medicine · Smoking Behavior and Cessation · Internal Medicine

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