Hospital Wastewater—Important Source of Multidrug Resistant Coliform Bacteria with ESBL-Production
Bibliographic Data
| ID | 15464469 |
|---|---|
| Authors | Kristína Lépesová (Slovak University of Technology in Bratislava), Petra Olejníková (0000-0001-9110-5526, Slovak University of Technology in Bratislava), Tomáš Mackuľak (Slovak University of Technology in Bratislava), Klára Cverenkárová (Slovak University of Technology in Bratislava), Monika Krahulcová (0000-0002-3573-5213, Slovak University of Technology in Bratislava), Lucia Bírošová (0000-0001-5221-0251, Slovak University of Technology in Bratislava, corresponding author) |
| Year | 2020 |
| Volume | 17 |
| Issue | 21 |
| Pages | 7827-7827 |
| Publication date | 2020-10-26 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | International Journal of Environmental Research and Public Health (JOURNAL) |
| Journal identifiers | ISSN: 1661-7827 • E-ISSN: 1660-4601 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/ijerph17217827 |
| PMID | 33114613 |
| OpenAlex | W3095732361 |
| Language | EN |
| Citations received | 2 |
| References cited | 1 |
This work compares the prevalence of antibiotic resistant coliform bacteria in hospital wastewater effluents in Slovak (SR) and Czech Republic (ČR). It also describes selected antibiotic resistant isolates in view of resistance mechanism and virulence factor. The highest number of multidrug resistant bacteria was detected in samples from the hospital in Valašské Meziříčí (ČR). More than half of resistant isolates showed multidrug resistance phenotype as well as strong ability to form biofilm. In 42% of isolates efflux pump overproduction was detected together with tetA and tetE genes. The production of extended-spectrum β-lactamases in coliform isolates was encoded mainly by bla TEM , bla CTX-M-2 and bla CTX-M-8/25 genes. About 62% of resistants contained a combination of two or more extended spectrum beta-lactamases (ESBL) genes. Our results strengthen the fact that hospital effluents are a source of multidrug resistant bacteria which can spread their resistance genes to other bacteria in wastewater treatment plants (WWTPs). Accordingly, hospital wastewater should be better treated before it enters urban sewerage
Antibiotic resistance · Antibiotics · Bacteria · Biology · Coliform bacteria · Effluent · Efflux · Gene · Multiple drug resistance · Plasmid · Sewerage · Wastewater · Antibiotic Resistance in Bacteria · Bacterial biofilms and quorum sensing · Environmental Science · Pharmaceutical and Antibiotic Environmental Impacts · Environmental Engineering · Genetics · Microbiology
| Citations per year | 0.5 |
|---|---|
| Citation span | 2022 - 2025 (4) |
| Highly cited | No |