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Effects of Maternal Prenatal Multi-Micronutrient Supplementation on Growth and Development until 3 Years of Age

Bibliographic Data

ID15468720
AuthorsGang Cheng (0000-0002-1760-9539, Central South University), Tingting Sha (0000-0002-8559-2150, Central South University), Xiao Gao (0000-0003-4042-8362, Central South University), Xialing Wu (0000-0003-0639-9860, Central South University), Qianling Tian (0000-0003-3104-2695, Central South University), Fan Yang (0000-0003-2978-7102, Central South University), Yan Yan (0000-0001-5357-0187, Central South University, corresponding author)
Year2019
Volume16
Issue15
Pages2744-2744
Publication date2019-08-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph16152744
PMID31374808
OpenAlexW2966034568
LanguageEN
Citations received1
References cited36

At present, there is insufficient evidence on whether prenatal multi-micronutrient (MM) supplementation can be an antenatal nutritional intervention or not. This study aimed to explore the sustained effect of prenatal MM supplementation on early childhood health. A total of 939 mother-offspring pairs were followed up in the study between 2015 to 2018 in Changsha, China. Information was mainly collected through household surveys at the ages of 1, 3, 6, 8, 12, 18, 24, and 36 months. General linear models and generalized estimating equation models were used to estimate the effects of maternal prenatal MM compared with IFA supplementation on infant growth and development. Offspring of women who used prenatal MM compared with IFA supplements had lower weight-for-age z score (WAZ) (adjusted β: -0.23, 95% CI: (-0.40, -0.06)) and weight-for-length z score (WLZ) (adjusted β: -0.20, 95% CI: (-0.37, -0.02)) at 3 months old, but a reduced risk of obesity at birth (aRR: 0.30, 95% CI: 0.11-0.78) and being overweight at 3 months old (aRR: 0.52, 95% CI: 0.32-0.84). Moreover, offspring of women who used prenatal MM compared with IFA supplements had significantly higher scores for communication (adjusted β: 0.41, 95% CI: 0.61-0.21), gross motor (adjusted β: 0.68, 95% CI: 0.49-0.88), fine motor (adjusted β: 1.64, 95% CI: 1.45-1.84), problem solving (adjusted β: 0.29, 95% CI: 0.10-0.49), and personal-social (adjusted β: 0.90, 95% CI: 0.70-1.10) skills at 36 months old. Prenatal MM supplementation could result in better infant growth in the first few months of life and improve development scores at the age of 3 years compared with IFA supplementation

Environmental health · Micronutrient · Birth, Development, and Health · Child Nutrition and Water Access · Folate and B Vitamins Research · Medicine · Physiology

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    Open Access•Maureen M Black, Susan P Walker et al.•The Lancet•2017

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Unique citing works1
Citations per year0,14
Citation span2019 - 2019 (1)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 1

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