The Impact of Acute Kidney Injury in the Perioperative Period on the Incidence of Postoperative Delirium in Patients Undergoing Coronary Artery Bypass Grafting—Observational Cohort Study
Bibliographic Data
| ID | 15470706 |
|---|---|
| Authors | Katarzyna Kotfis (0000-0001-8430-1369, Pomeranian Medical University, corresponding author), Justyna Ślozowska (0000-0003-4885-9757, Pomeranian Medical University), Mariusz Listewnik (0000-0002-5614-3209, Pomeranian Medical University), Aleksandra Szylińska (0000-0001-6105-5329, Pomeranian Medical University), Iwona Rotter (0000-0002-4337-6476, Pomeranian Medical University) |
| Year | 2020 |
| Volume | 17 |
| Issue | 4 |
| Pages | 1440-1440 |
| Publication date | 2020-02-24 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | International Journal of Environmental Research and Public Health (JOURNAL) |
| Journal identifiers | ISSN: 1661-7827 • E-ISSN: 1660-4601 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/ijerph17041440 |
| PMID | 32102286 |
| OpenAlex | W3006888152 |
| Language | EN |
| References cited | 23 |
Recent data indicate that acute kidney damage leads to inflammation in the brain and other distant organs. The purpose of this study was to investigate the effect of acute kidney injury (AKI) according to the Kidney Disease Improving Global Outcome (KDIGO) criteria on the occurrence of postoperative delirium in patients undergoing coronary artery bypass grafting (CABG). We performed a retrospective cohort analysis that included all consecutive patients undergoing elective CABG. The CAM-ICU (Confusion Assessment Method for Intensive Care Unit) was used for delirium assessment. Patients were divided into four groups, depending on the occurrence of AKI in the perioperative period according to KDIGO criteria. Overall, 902 patients were included in the final analysis, the mean age was 65.95 ± 8.01 years, and 76.83% were males (693/957). The majority of patients presented with normal kidney function-baseline creatinine level of 0.91 ± 0.21 (mg/dL). The incidence of AKI in the perioperative setting was 22.17% (200/902). Postoperative delirium was diagnosed in 115/902 patients (12.75%). Compared with no AKI, the odds of developing POD were increased for KDIGO stage 1 (OR 2.401 (95% confidence interval 1.484-3.884), p p = 0.005); and highest for KDIGO stage 3 (OR equal to 9.729 (95% confidence interval 2.675-35.382), p = 0.001). Acute kidney injury, based on AKI staging, should be regarded as an independent risk factor for postoperative delirium after cardiac surgery
Acute kidney injury · Anesthesia · Confidence interval · Delirium · Incidence (geometry · Intensive care medicine · Intensive care unit · Kidney disease · Odds ratio · Perioperative · Retrospective cohort study · Acute Kidney Injury Research · Anesthesia and Neurotoxicity Research · Intensive Care Unit Cognitive Disorders · Medicine · Internal Medicine · Surgery
| Citation velocity | historical |
|---|---|
| Highly cited | No |