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Italian Children Exposure to Bisphenol A

Biomonitoring Data from the Life Persuaded Project

Bibliographic Data

ID15474187
AuthorsSabrina Tait (0000-0001-8029-8625, Istituto Superiore di Sanità), Fabrizia Carli (0000-0003-2540-1110, Istituto di Fisiologia Clinica), Luca Busani (0000-0002-6081-2794, Istituto Superiore di Sanità), Demetrio Ciociaro (0009-0001-4701-0586, Istituto di Fisiologia Clinica), Veronica Della Latta (0000-0002-9240-8921, Istituto di Fisiologia Clinica), Annalisa Deodati (0000-0001-8636-382X, Bambino Gesù Children's Hospital), Enrica Fabbrizi (0000-0002-2104-1720, L'organizzazione Ospedale di Civitanova M), Anna Paola Pala (Istituto di Fisiologia Clinica), Francesca Maranghi (0000-0003-1736-2262, Istituto Superiore di Sanità), Roberta Tassinari (0000-0002-4121-2144, Istituto Superiore di Sanità), Giacomo Toffol (0000-0003-4402-0524, Associazione Culturale Pediatri, Via Montiferru, 6, 09070 Narbolia, Italy), Stefano Cianfarani (0000-0002-2580-8781, University of Rome Tor Vergata), Amalia Gastaldelli (0000-0003-2594-1651, Istituto di Fisiologia Clinica), Cinzia La Rocca (0000-0002-5179-554X, Istituto Superiore di Sanità, corresponding author)
Year2021
Volume18
Issue22
Pages11846-11846
Publication date2021-11-11
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph182211846
PMID34831602
OpenAlexW3214652123
LanguageEN
References cited37

A human biomonitoring (HBM) study on bisphenol A (BPA) in Italian children and adolescents was performed within the LIFE PERSUADED project, considering the residing areas, sex and age. The median urinary BPA level was 7.02 μg/L, with children living in the South of Italy or in urban areas having higher levels than those residing in the North or in rural areas. Children aged 4-6 years had higher BPA levels than those aged 7-10 and 11-14 years, but no differences were detected between sexes. The exposure in Italian children was higher compared to children from other countries, but lower than the HBM guidance value (135 μg/L). The estimated daily intake was 0.17 μg/kg body weight (bw) per day, about 24-fold below the temporary Tolerable Daily Intake of 4 μg/kg bw per day established by the European Food Safety Authority. However, this threshold was exceeded in 1.44% of the enrolled children, raising concern about the overall exposure of Italian young population

Biomonitoring · Environmental health · Chemistry · Effects and risks of endocrine disrupting chemicals · Environmental Science · Medicine · Toxic Organic Pollutants Impact · Environmental Chemistry

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