Predictors of Lung Cancer Risk
An Ecological Study Using Mortality and Environmental Data by Municipalities in Italy
Bibliographic Data
Lung cancer (LC) mortality remains a consistent part of the total deaths occurring worldwide. Its etiology is complex as it involves multifactorial components. This work aims in providing an epidemiological assessment on occupational and environmental factors associated to LC risk by means of an ecological study involving the 8092 Italian municipalities for the period 2006-2015. We consider mortality data from mesothelioma as proxy of asbestos exposure, as well as PM 2.5 and radon levels as a proxy of environmental origin. The compensated cases for occupational respiratory diseases, urbanization and deprivation were included as predictors. We used a negative binomial distribution for the response, with analysis stratified by gender. We estimated that asbestos is responsible for about 1.1% (95% CI: 0.8, 1.4) and 0.5% (95% CI: 0.2, 0.8) of LC mortality in males and females, respectively. The corresponding figures are 14.0% (95% CI: 12.5, 15.7) and 16.3% (95% CI: 16.2, 16.3) for PM 2.5 exposure, and 3.9% (95% CI: 3.5, 4.2) and 1.6% (95% CI: 1.4, 1.7) for radon exposure. The assessment of determinants contribution to observed LC deaths is crucial for improving awareness of its origin, leading to increase the equity of the welfare system
Biology · Ecological study · Environmental health · Geography · Lung cancer · Population · Sociology · Air Quality and Health Impacts · Air Quality Monitoring and Forecasting · Climate Change and Health Impacts · Demography · Medicine · Ecology · Oncology
Analysis of Panel Data
Estimates and 25-year trends of the global burden of disease attributable to ambient air pollution
Global, regional, and national age-sex specific mortality for 264 causes of death, 1980–2016
The carcinogenicity of outdoor air pollution
Long-term exposure to PM and all-cause and cause-specific mortality
Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-years for 32 Cancer Groups, 1990 to 2015
Radon, Smoking, and Lung Cancer
| Citations per year | 0.5 |
|---|---|
| Citation span | 2024 - 2024 (1) |
| Highly cited | No |