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Clinical Symptom Patterns as Predictors of Sars-CoV-2 Infection in Healthcare Workers in Puerto Rico

Bibliographic Data

ID15484773
AuthorsDaniela Ortiz (0000-0003-4185-7601, University of Puerto Rico at Río Piedras, corresponding author), Desiré Vázquez Ortiz (Department of Mathematics, University of Puerto Rico, Rio Piedras Campus, San Juan, PR 00931, USA), Josefina Romaguera (0000-0001-5403-9160, University of Puerto Rico System), Jean L Santos Agrait (University of Puerto Rico System), Fernando Vázquez (0000-0002-2352-5956, University of Puerto Rico, Medical Sciences Campus), Frances Vázquez (Department of Microbiology and Immunology, University of Puerto Rico, Medical Sciences Campus, San Juan, PR 00918, USA), María-Eglée Pérez (0000-0001-8641-8405, University of Puerto Rico at Río Piedras), Carmen Zorrilla (0000-0001-7740-1636, University of Puerto Rico System), Filipa Godoy‐Vitorino (0000-0003-1880-0498, University of Puerto Rico, Medical Sciences Campus)
Year2025
Volume23
Issue1
Pages8-8
Publication date2025-12-19
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph23010008
PMID41595801
OpenAlexW4417503124
LanguageEN
References cited20

Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, has posed major risks for healthcare workers (HCWs) worldwide. This study assessed the prevalence of infection and its relationship with demographic and clinical characteristics among HCWs at the University of Puerto Rico Adult Hospital. A total of 132 individuals were enrolled, of whom six tested positive (4.55%). The study population was predominantly female (78.8%) with a mean age of 41 years, and although men showed higher odds of infection (OR = 3.98), the difference was not significant. Symptom presence was strongly associated with infection: 7.4% of symptomatic participants tested positive compared to none of the asymptomatic ( p p = 0.002), taste loss (OR = 24.20, p = 0.002), smell loss (OR = 15.25, p = 0.024), and fever (OR = 20.50, p = 0.016) were significantly linked to infection, while others such as headache and congestion were not. These findings underscore the utility of symptom-based monitoring in occupational health, though the single-site design, modest sample size, reliance on self-report, and early pandemic diagnostic limitations may have led to underestimation of true cases

Asymptomatic · Cross-sectional study · Disease · Health care · Odds · Odds ratio · Pandemic · Population · Prevalence · COVID-19 and Mental Health · Infection Control and Ventilation · Long-Term Effects of COVID-19

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    Open Access•Kuan-Fu Chen, Tsai-Wei Feng et al.•Journal of Global Health•2023

Highly citedNo

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