Occupational Exposure in the Lombardy Region (Italy) to Sars-CoV-2 Infection

Results From the Mustang–occupation–covid-19 Study

Bibliographic Data

ID15486240
AuthorsPaola Della Valle (0000-0002-6484-9674, MultiMedica), Marco Fabbri (0000-0002-7248-4214, MultiMedica), Fabiana Madotto (0000-0002-8829-9160, MultiMedica, corresponding author), Pietro Ferrara (0000-0001-9449-3464, MultiMedica, corresponding author), Paolo Cozzolino (0000-0001-6178-8581, MultiMedica), Elisabetta Calabretto (MultiMedica), Marco D’Orso (Consortium for Occupational and Environmental Medicine, Department of Medicine and Surgery, University of Milan–Bicocca, 20900 Monza, Italy), Ermanno Longhi (MultiMedica), Riccardo Polosa (0000-0002-8450-5721, University of Catania), M Riva (0000-0001-7147-3460, University of Milano-Bicocca), Giampiero Mazzaglia (0000-0003-4933-2148, University of Milano-Bicocca), Carmen Sommese (MultiMedica), LG Mantovani (0000-0003-3866-8199, MultiMedica), Lorenzo Mantovani (Center for Public Health Research, University of Milan Bicocca, 20900 Monza, Italy)
Year2021
Volume18
Issue5
Pages2567-2567
Publication date2021-03-04
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph18052567
PMID33806578
OpenAlexW3134261582
LanguageEN
Citations received2
References cited27

Sero-epidemiological surveys are valuable attempts to estimate the circulation of SARS-CoV-2 in general or selected populations. Within this context, a prospective observational study was conducted to estimate the prevalence and persistence of SARS-CoV-2 antibodies in different categories of workers and factors associated with positivity, through the detection of virus-specific immunoglobulin G and M (IgG/IgM) in serum samples. Enrollees were divided in low exposure and medium-high groups on the basis of their work activity. Antibody responders were re-contacted after 3 months for the follow-up. Of 2255 sampled workers, 4.8% tested positive for SARS-CoV-2 IgG/IgM antibodies, with 81.7% to IgG only. Workers who continued to go to their place of work, were healthcare workers, or experienced at least one COVID-19-related symptom were more likely to test positive for SARS-CoV-2 antibodies. SARS-CoV-2 antibodies prevalence was significantly higher in the medium-high risk vs. low-risk group (7.2% vs. 3.0%, p < 0.0001). At 3-month follow-up, 81.3% of subjects still had antibody response. This study provided important information of SARS-CoV-2 infection prevalence among workers in northern Italy, where the impact of COVID-19 was particularly intense. The presented surveillance data give a contribution to refine current estimates of the disease burden expected from the SARS-CoV-2

2019-20 coronavirus outbreak · Betacoronavirus · Coronavirus disease 2019 (COVID-19 · Coronavirus Infections · Environmental health · Infectious disease (medical specialty · Occupational exposure · Outbreak · Pathology · Sars virus · Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 · COVID-19 and Mental Health · Infection Control and Ventilation · Long-Term Effects of COVID-19 · Medicine · Virology

Tools

Open DOIOpen Access