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Quality of Life in a Cohort of 1078 Women Diagnosed with Breast Cancer in Spain

7-Year Follow-Up Results in the MCC-Spain Study

Bibliographic Data

ID15488982
AuthorsJéssica Alonso-Molero (0000-0002-1939-8798, Universidad de Cantabria, corresponding author), Trinidad Dierssen-Sotos (Department of Preventive Medicine and Public Health, University of Cantabria—IDIVAL, 39011 Santander, Spain), Trinidad Dierssen‐Sotos (0000-0002-6127-0077, Universidad de Cantabria), Inés Gómez‐Acebo (0000-0001-8793-8314, Universidad de Cantabria), Inés Gómez-Acebo (Department of Preventive Medicine and Public Health, University of Cantabria—IDIVAL, 39011 Santander, Spain), Nerea Fernández de Larrea Baz (Instituto de Salud Carlos III), Marcela Guevara (0000-0001-9242-6364, Instituto de Salud Pública de Navarra), Pilar Amiano (0000-0003-3986-7026, Biogipuzkoa Health Research Institute), Gemma Castaño‐Vinyals (0000-0003-4468-1816, Hospital Del Mar), Tania Fernández‐Villa (0000-0002-9049-3026, Universidad de León), Victor Moreno (0000-0002-2818-5487, Institut d'Investigació Biomédica de Bellvitge), Juan L Bayo (0000-0002-3428-5708, Hospital Juan Ramón Jiménez), Juan Bayo (Servicio de Oncología del Hospital Universitario Juan Ramón Jiménez, 21005 Huelva, Spain), Ana Molina‐Barceló (0000-0001-5113-6475, Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana), Ana Molina-Barceloa (Cancer and Public Health Area, FISABIO—Public Health, 46035 Valencia, Spain), María Fernández-Ortiz (0000-0003-0017-875X, Universidad de Cantabria), Claudia Suárez-Calleja (Universidad de Oviedo), Rafael Marcos-Gragera (0000-0001-9824-3657, Generalitat de Catalunya), Xavier Castells (0000-0002-2619-7273, Spanish Clinical Research Network), Leire Gil-Majuelo (Biogipuzkoa Health Research Institute), Eva Ardanaz (0000-0001-8434-2013, Instituto de Salud Pública de Navarra), Beatriz Pérez‐gómez (0000-0002-4299-8214, Instituto de Salud Carlos III), Manolis Kogevinas (0000-0002-9605-0461, Hospital Del Mar), M Pollán (0000-0002-4328-1565, Instituto de Salud Carlos III), Javier Llorca (0000-0001-8569-861X, Universidad de Cantabria)
Year2020
Volume17
Issue22
Pages8411-8411
Publication date2020-11-13
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph17228411
PMID33202919
OpenAlexW3105769583
LanguageEN
Citations received3
References cited32

Breast cancer is the most frequent cause of tumors and net survival is increasing. Achieving a higher survival probability reinforces the importance of studying health-related quality of life (HR-QoL). The main aim of this work is to test the relationship between different sociodemographic, clinical and tumor-intrinsic characteristics, and treatment received with HR-QoL measured using SF-12 and the FACT/NCCN (National Comprehensive Cancer Network/Functional Assessment of Cancer Therapy) Breast Symptom Index (FBSI). Women with breast cancer recruited between 2008 and 2013 and followed-up until 2017-2018 in a prospective cohort answered two HR-QoL surveys: the SF-12 and FBSI. The scores obtained were related to woman and tumor characteristics using linear regression models. The telephone survey was answered by 1078 women out of 1685 with medical record follow-up (64%). Increases in all three HR-QoL scores were associated with higher educational level. The score differences between women with university qualifications and women with no schooling were 5.43 for PCS-12, 6.13 for MCS-12 and 4.29 for FBSI. Histological grade at diagnosis and recurrence in the follow-up displayed a significant association with mental and physical HR-QoL, respectively. First-line treatment received was not associated with HR-QoL scores. On the other hand, most tumor characteristics were not associated with HR-QoL. As breast cancer survival is improving, further studies are needed to ascertain if these differences still hold in the long run

Breast cancer · Cancer · Cohort · Cohort study · Physical therapy · Prospective cohort study · Quality of life (healthcare · Telephone interview · Breast Cancer Treatment Studies · Cancer survivorship and care · Global Cancer Incidence and Screening · Medicine · Gerontology · Internal Medicine · Oncology

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Unique citing works3
Citations per year0.75
Citation span2022 - 2025 (4)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 3

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