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Behavioral Factors Associated with Medication Nonadherence in Patients with Hypertension

Bibliographic Data

ID15499668
AuthorsShu‐Mei Chang (0000-0002-5649-6055, E-Da Hospital), Shu-Mei Chang (Outpatient Department, E-DA Dachang Hospital, Kaohsiung 80794, Taiwan), I‐Cheng Lu (0000-0001-6643-1071, E-Da Hospital), I-Cheng Lu (0000-0003-1959-0015, Department of Occupational Medicine, E-Da Hospital, Kaohsiung 82445, Taiwan), Yi‐chun Chen (0000-0001-7997-8578, Ministry of Health and Welfare, corresponding author), Yi-Chun Chen (0000-0002-3682-6168, I-Shou University), Chin‐Feng Hsuan (0000-0002-0562-8310, E-Da Hospital), Yin-Jin Lin (E-Da Hospital), Hung-Yi Chuang (0000-0002-8321-8720, Kaohsiung Medical University)
Year2021
Volume18
Issue18
Pages9614-9614
Publication date2021-09-12
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph18189614
PMID34574540
OpenAlexW3201214699
LanguageEN
Citations received1
References cited22

Medication nonadherence is associated with an increased risk of complications in hypertensive patients. We investigated behavioral factors associated with medication nonadherence in hypertensive patients in southern Taiwan. Using questionnaires, we collected data regarding clinicodemographic characteristics and nonadherence behaviors from 238 hypertensive patients. We assessed the self-reported prevalence of specific behaviors of medication nonadherence and investigated factors associated with each behavior using multivariable logistic regression analysis. The most common behavior of medication nonadherence was forgetting to take medication (28.6%), followed by discontinuing medication (9.2%) and reducing the medication dose (8.8%). Age ≥ 65 years (adjusted odds ratio [aOR] = 0.32, 95% confidence interval [CI] = 0.15-0.69) and male sex (aOR = 2.61, CI = 1.31-5.19) were associated with forgetting to take medication. The presence of comorbidities (diabetes, kidney disease, or both) and insomnia (aOR = 3.97, 95% CI = 1.30-12.1) was associated with reducing the medication dose. The use of diet supplements was associated with discontinuing the medication (aOR = 4.82, 95% CI = 1.50-15.5). Compliance with a low oil/sugar/sodium diet was a protective factor against discontinuing medication (aOR = 0.14; 95% CI = 0.03-0.75). The most pervasive behavior associated with medication nonadherence among hypertensive patients was forgetting to take medication. Age <65 years, male sex, comorbidities, insomnia, noncompliance with diet, and the use of dietary supplements were specifically associated with medication nonadherence

Biology · Medication adherence · MEDLINE · Blood Pressure and Hypertension Studies · Medication Adherence and Compliance · Medicine · Pharmaceutical Practices and Patient Outcomes · Internal Medicine

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Unique citing works1
Citations per year0,25
Citation span2022 - 2022 (1)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 1

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