Sars-CoV-2 Viral Load Analysis at Low and High Altitude
A Case Study from Ecuador
Bibliographic Data
| ID | 15511016 |
|---|---|
| Authors | Esteban Ortiz-Prado (0000-0002-1895-7498, Universidad de Las Américas, corresponding author), Katherine Simbaña‐Rivera (0000-0002-8130-5361, Universidad de Las Américas), Raúl Fernández-Naranjo (0000-0002-4875-9652, Universidad de Las Américas), Jorge Vasconez-Gonzalez (0000-0003-4573-6217, Universidad de Las Américas), Aquiles R Henríquez-Trujillo (0000-0002-3094-4438, Universidad de Las Américas), Alexander Paolo Vallejo-Janeta (0000-0002-4144-595X, Universidad de Las Américas), Ismar A Rivera‐Olivero (0000-0001-8345-8217, Universidad de Las Américas), Tannya Lozada (0000-0001-5043-9431, Universidad de Las Américas), Ginés Viscor (0000-0003-4942-2346, Universitat de Barcelona), Miguel Ángel García-Bereguiain (0000-0003-0025-3609, Universidad de Las Américas) |
| Year | 2022 |
| Volume | 19 |
| Issue | 13 |
| Pages | 7945-7945 |
| Publication date | 2022-06-28 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | International Journal of Environmental Research and Public Health (JOURNAL) |
| Journal identifiers | ISSN: 1661-7827 • E-ISSN: 1660-4601 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/ijerph19137945 |
| PMID | 35805606 |
| OpenAlex | W4283710277 |
| Language | EN |
| Citations received | 1 |
| References cited | 36 |
SARS-CoV-2 has spread throughout the world, including remote areas such as those located at high altitudes. There is a debate about the role of hypobaric hypoxia on viral transmission and COVID-19 incidence. A descriptive cross-sectional analysis of SARS-CoV-2 infection and viral load among patients living at low (230 m) and high altitude (3800 m) in Ecuador was completed. Within these two communities, the total number of infected people at the time of the study was 108 cases (40.3%). The COVID-19 incidence proportion at low altitude was 64% while at high altitude was 30.3%. The mean viral load from those patients who tested positive was 3,499,184 copies/mL (SD = 23,931,479 copies/mL). At low altitude (Limoncocha), the average viral load was 140,223.8 copies/mL (SD = 990,840.9 copies/mL), while for the high altitude group (Oyacachi), the mean viral load was 6,394,789 copies/mL (SD = 32,493,469 copies/mL). We found no statistically significant differences when both results were compared ( p = 0.056). We found no significant differences across people living at low or high altitude; however, men and younger populations had higher viral load than women older populations, respectively
Altitude (triangle · Biology · Coronavirus disease 2019 (COVID-19 · Effects of high altitude on humans · Hypoxia (environmental · Incidence (geometry · Infectious disease (medical specialty · Low altitude · Oxygen · Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 · Transmission (telecommunications · Veterinary medicine · Viral load · Virus · Chemistry · COVID-19 and Mental Health · COVID-19 epidemiological studies · Long-Term Effects of COVID-19 · Mathematics · Medicine · Internal Medicine · Virology
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| Unique citing works | 1 |
|---|---|
| Citations per year | 0.25 |
| Citation span | 2022 - 2022 (1) |
| Citation velocity | historical |
| Highly cited | No |
| Citation types | Neutral: 1 |