Assessing Global Frailty Scores
Development of a Global Burden of Disease-Frailty Index (GBD-FI)
Bibliographic Data
| ID | 15514876 |
|---|---|
| Authors | Mark O’Donovan (0000-0001-8498-7567, National University of Ireland), Duygu Sezgin (0000-0001-8378-6835, National University of Ireland), Zubair Kabir (0000-0003-1529-004X, University College Cork), Aaron Liew (0000-0002-6274-0253, National University of Ireland), Rónán Ó’Caoimh (0000-0002-1499-673X, National University of Ireland, corresponding author) |
| Year | 2020 |
| Volume | 17 |
| Issue | 16 |
| Pages | 5695-5695 |
| Publication date | 2020-08-06 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | International Journal of Environmental Research and Public Health (JOURNAL) |
| Journal identifiers | ISSN: 1661-7827 • E-ISSN: 1660-4601 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/ijerph17165695 |
| PMID | 32781756 |
| OpenAlex | W3042140215 |
| Language | EN |
| Citations received | 1 |
| References cited | 51 |
Frailty is an independent age-associated predictor of morbidity and mortality. Despite this, many countries lack population estimates with large heterogeneity between studies. No population-based standardised metric for frailty is available. We applied the deficit accumulation model of frailty to create a frailty index (FI) using population-level estimates from the Global Burden of Disease (GBD) 2017 study across 195 countries to create a novel GBD frailty index (GBD-FI). Standard FI criteria were applied to all GBD categories to select GBD-FI items. Content validity was assessed by comparing the GBD-FI with a selection of established FIs. Properties including the rate of deficit accumulation with age were examined to assess construct validity. Linear regression models were created to assess if mean GBD-FI scores predicted one-year incident mortality. From all 554 GBD items, 36 were selected for the GBD-FI. Face validity against established FIs was variable. Characteristic properties of a FI-higher mean score for females and a deficit accumulation rate of approximately 0.03 per year, were observed. GBD-FI items were responsible for 19% of total Disability-Adjusted Life Years for those aged ≥70 years in 2017. Country-specific mean GBD-FI scores ranged from 0.14 (China) to 0.19 (Hungary) and were a better predictor of mortality from non-communicable diseases than age, gender, Healthcare Access and Quality Index or Socio-Demographic Index scores. The GBD-FI is a valid measure of frailty at population-level but further external validation is required
Burden of disease · Environmental health · Frailty Index · Index (typography · Metric (unit · Population · Computer Science · Demography · Frailty in Older Adults · Health Systems, Economic Evaluations, Quality of Life · Medicine · Nutrition and Health in Aging · Gerontology
Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016
Prevalence of Frailty in Community‐Dwelling Older Persons
Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017
Estimates of global, regional, and national morbidity, mortality, and aetiologies of diarrhoeal diseases
Frailty in elderly people
Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations
Accumulation of Deficits as a Proxy Measure of Aging
A standard procedure for creating a frailty index
Measuring population ageing
Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015
Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017
Modelling and prediction of global non-communicable diseases
| Citations per year | 1 |
|---|---|
| Citation span | 2026 - 2026 (1) |
| Highly cited | No |