Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015

Bibliographic Data

ID23331969
AuthorsGregory A Roth (0000-0002-8355-9146, University of Washington, corresponding author), Catherine Johnson (0000-0001-9809-4444), Catherine O Johnson (University of Washington), Amanuel Alemu Abajobir (0000-0002-6878-0627, The University of Queensland), Amanuel Abajobir, Foad Abd-Allah (0000-0001-8308-5756, Cairo University), Semaw Ferede Abera (0000-0002-9284-1231, Mekelle University), Gebre Yitayih Abyu (Mekelle University), Gebre Abyu, Muktar Beshir Ahmed (0000-0002-9524-7027, Jimma University), Muktar Ahmed, Baran Aksut (0000-0001-5598-819X, Cleveland Clinic), Shazia Alam (0000-0003-2606-9463, University of Washington), Tahiya Alam, Khurshid Alam (0000-0002-7402-7519, The University of Melbourne), François Alla (0000-0002-5793-7190, Université de Lorraine), Nelson Alvis-Guzman (0000-0001-9458-864X, University of Cartagena), Stephen Amrock, Stephen M Amrock (0000-0002-4394-4015, Oregon Health & Science University), Hossein Ansari (0000-0003-2755-7864, Zahedan University of Medical Sciences), Johan Ärnlöv (0000-0002-6933-4637, Uppsala University), Hamid Asayesh (0000-0002-9916-9476, Qom University of Medical Science and Health Services), Tesfay Mehari Atey (0000-0002-6483-2258, Mekelle University), Leticia Ávila‐Burgo (0000-0002-8292-7103, Instituto Nacional de Salud Pública), Leticia Avila-Burgos, Ashish Awasthi (0000-0002-9308-9782, Sanjay Gandhi Post Graduate Institute of Medical Sciences), Amitava Banerjee (0000-0001-8741-3411, University College London), Aleksandra Barać (0000-0002-0132-2277, University of Peradeniya), Till Bärnighausen (0000-0002-4182-4212, Harvard University Press), Lars Barregård (0000-0002-4662-0841, Bispebjerg Hospital), Neeraj Bedi (0000-0003-4709-8423, Jazan University), Ezra B Ketema (0000-0001-6546-0591, Deakin University), Derrick Bennett (0000-0002-9170-8447, Auckland University of Technology), Gebremedhin Berhe (Mekelle University), Zulfiqar A Bhutta (0000-0003-0637-599X, Aga Khan University), Zulfiqar Bhutta, Shimelash Bitew Workie (0000-0002-6159-6309, Wolaita Sodo University), Shimelash Bitew, Jonathan R Carapetis (0000-0002-1182-9792, The University of Western Australia), Jonathan Carapetis, Juan Jesus Carrero (0000-0003-4763-2024, Karolinska Institutet), Deborah Carvalho Malta (0000-0002-8214-5734, Universidade Federal de Minas Gerais), Carlos Andrés Castañeda-Orjuela, Carlos Castañeda Orjuela (0000-0002-8735-6223, Instituto Nacional de Salud), Jacqueline Castillo-Rivas (University of Peradeniya), Ferrán Catalá-López (0000-0002-3833-9312, Universitat de València), Jee-Young Choi (Seoul National University Hospital), Hanne Christensen (0000-0002-7472-3194, Bispebjerg Hospital), Massimo Cirillo (0000-0002-6409-3504, University of Peradeniya), Lauren T Cooper (0000-0003-1002-3313, Mayo Clinic), Leslie Cooper, Michael H Criqui (0000-0003-0425-9661, Deakin University), Michael Criqui, David K Cundiff (0000-0002-3206-9665, University of Salerno), David Cundiff, Albertino Damasceno (0000-0003-0925-494X, Deakin University), Lalit Dandona (0000-0002-3114-8628, University of Washington), Rakhi Dandona (0000-0003-0926-788X, Deakin University), Kairat Davletov (0000-0001-8534-1899, University of Peradeniya), Samath Dhamminda Dharmaratne (0000-0003-4144-2107, University of Peradeniya), Samath Dharmaratne, Prabhakaran Dorairaj (Centre for Chronic Disease Control), Manisha Dubey (0000-0003-2879-903X, International Institute for Population Sciences), Rebecca Ehrenkranz (0000-0003-2810-6045, Universitat de València), Maysaa El Sayed Zaki (0000-0001-5431-0248, Mansoura University), Emerito Jose A Faraon (0000-0001-6157-5930, Deakin University), Alireza Esteghamati (0000-0001-5114-3982, Tehran University of Medical Sciences), Talha Farid (University of Louisville), Maryam S Farvid (0000-0003-1783-4186, Harvard University Press), Maryam Farvid, Valery L Feigin (0000-0002-6372-1740, Auckland University of Technology), Valery Feigin, Eric L Ding (0000-0002-5881-8097, Harvard University Press), Gerry Fowkes (University of Massachusetts Boston), Tsegaye Gebrehiwot (Jimma University), Richard F Gillum (0000-0002-9157-3837, University of Peradeniya), Richard Gillum, Audra Gold, Audra L Gold (University of Washington), Philimon Gona (0000-0002-4202-5965, Deakin University), Rajeev Gupta (0000-0002-8356-3137, Bispebjerg Hospital), Tesfa Dejenie Habtewold (0000-0003-4476-518X, University of Groningen), Nima Hafezi‐nejad (0000-0001-9052-450X, Tehran University of Medical Sciences), Nima Hafezi-Nejad, Tesfaye Hailu (0000-0001-6019-5864, University of Louisville), Gessessew Bugssa Hailu (University of Louisville), Graeme J Hankey (0000-0002-6044-7328, University of Louisville), Graeme Hankey, Hamid Yimam Hassen (0000-0001-6485-4193, University of Louisville), Kalkidan Hassen Abate (0000-0003-3486-2111, Jimma University), Rasmus Havmoeller (University of Peradeniya), Simon I Hay (0000-0002-0611-7272, University of Washington), Masako Horino (0000-0001-6544-1622, Deakin University), Peter J Hotez (0000-0001-8770-1042, Baylor College of Medicine), Klaus H Jacobsen (0000-0002-4198-6246, George Mason University), Kathryn Jacobsen, Spencer James, Spencer L James (0000-0003-4653-2507, Universitat de València), Mehdi Javanbakht (0000-0002-8661-8439, Universitat de València), Panniyammakal Jeemon (0000-0003-4172-4307, Bispebjerg Hospital), Denny John (0000-0002-4486-632X, University of Washington), Jost B Jonas (0000-0003-2972-5227, University of Salerno), Jost Jonas, Yogeshwar Kalkonde (0000-0003-3543-3618, University of Salerno), Chante Karimkhani (0000-0003-2347-7576, Mayo Clinic), Amir Kasaeian (0000-0003-2018-9368, Tehran University of Medical Sciences), Yousef Khader (0000-0002-7830-6857, Jordan University of Science and Technology), Abdur Rahman Khan (0000-0003-0464-6514, University of Louisville), Abdur Khan, Young-Ho Khang (0000-0002-9585-8266, University of Peradeniya), Sahil Khera (0000-0001-9777-5934, University of Peradeniya), Abdullah T Khoja (0000-0003-1844-3742, University of Peradeniya), Jagdish Khubchandani (0000-0002-9058-4278, Ball State University), Daniel Kim (0000-0003-0470-8279), Dhaval Kolte (0000-0002-7107-3667, Mansoura University), Soewarta Kosen (0000-0002-2517-8118, Mansoura University), Kristopher J Krohn (Deakin University), G Anil Kumar (0000-0002-7986-0905, Public Health Foundation of India), Gene F Kwan (0000-0002-0929-6800, Boston University), Dharmesh Kumar Lal (Tehran University of Medical Sciences), Anders Larsson (0000-0001-5754-4322, Uppsala University), Shai Linn (0000-0002-0867-2958, University of Louisville), Alan D Lopez (0000-0001-5818-6512, University of Louisville), Alan Lopez, Paulo A Lotufo (0000-0002-4856-8450, University of Louisville), Hassan Magdy Abd El Razek (0000-0002-8857-0408, Mansoura University), Reza Malekzadeh (0000-0003-1043-3814), Mohsen Mazidi (0000-0003-3059-229X), Toni Meier (0000-0001-6056-0665), Kidanu Gebremariam Meles, George Mensah (0009-0006-6280-5738), Atte Meretoja (0000-0001-6433-1931), Haftay Mezgebe, Ted Miller, Erkin Mirrakhimov, Shafiu Mohammed (0000-0001-5715-966X), Andrew E Moran (0000-0003-3554-0085), Kamarul Imran Musa (0000-0002-3708-0628), Jagat Narula (0000-0002-0280-3996), Bruce Neal (0000-0002-0490-7465), Frida Ngalesoni, Grant Nguyen, Carla Makhlouf Obermeyer, Mayowa Owolabi (0000-0003-1146-3070), George Patton (0000-0001-5039-8326), João Pedro (0000-0003-4471-7401), Dima Qato, Mostafa Qorbani (0000-0001-9465-7588), Kazem Rahimi (0000-0002-4807-4610), Rajesh Kumar Rai (0000-0002-2275-815X), Salman Rawaf (0000-0001-7191-2355), António Ribeiro (0000-0001-9614-9552), Saeid Safiri (0000-0001-7986-9072), Joshua A Salomon (0000-0003-3929-5515), Itamar Santos (0000-0001-5288-4846), Milena Santric Milicevic, Benn Sartorius (0000-0001-6761-2325), Aletta Schutte, Sadaf Sepanlou, Masood Ali Shaikh (0000-0003-0239-4464), Min-Jeong Shin, Mehdi Shishehbor, Hirbo Shore, Diego Augusto Santos Silva (0000-0002-0489-7906), Eugène Sobngwi (0000-0001-5457-6572), Saverio Stranges (0000-0001-5226-8373), Soumya Swaminathan (0000-0002-6896-2703), Rafael Tabarés-Seisdedos, Niguse Tadele Atnafu (0000-0002-3765-3617), Fisaha Tesfay, J S Thakur, Amanda Thrift, Roman Topór-Madry, Thomas Truelsen (0000-0001-6648-7761), Stefanos Tyrovolas (0000-0003-1498-0997), Kingsley Nnanna Ukwaja (0000-0002-1974-8735), Olalekan Uthman, Tommi Vasankari (0000-0001-7209-9351), Vasiliy Vlassov, Stein Emil Vollset, Tolassa Wakayo, David Watkins (0000-0002-3930-5990), Robert Weintraub, Andrea Werdecker, Ronny Westerman, Charles Shey Wiysonge (0000-0002-1273-4779), Charles Wolfe (0000-0001-8264-0981), Abdulhalik Workicho (0000-0001-8422-1983), Gelin Xu (0000-0002-6194-0341), Yuichiro Yano (0000-0002-2565-7290), Paul Yip (0000-0003-1596-4120), Naohiro Yonemoto (0000-0003-3637-2095), Mustafa Younis, Chuanhua Yu (0000-0002-5467-2481), Theo Vos (0000-0002-5690-5365), Mohsen Naghavi (0000-0003-3691-1458), Christopher Murray (0000-0003-0569-8658)
Year2017
Volume70
Issue1
Pages1-25
Publication date2017-07-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of the American College of Cardiology (JOURNAL)
Journal identifiersISSN: 0735-1097 • E-ISSN: 1558-3597
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jacc.2017.04.052
PMID28527533
OpenAlexW2614578122
LanguageEN
Citations received140
References cited46

BACKGROUND: The burden of cardiovascular diseases (CVDs) remains unclear in many regions of the world. OBJECTIVES: The GBD (Global Burden of Disease) 2015 study integrated data on disease incidence, prevalence, and mortality to produce consistent, up-to-date estimates for cardiovascular burden. METHODS: CVD mortality was estimated from vital registration and verbal autopsy data. CVD prevalence was estimated using modeling software and data from health surveys, prospective cohorts, health system administrative data, and registries. Years lived with disability (YLD) were estimated by multiplying prevalence by disability weights. Years of life lost (YLL) were estimated by multiplying age-specific CVD deaths by a reference life expectancy. A sociodemographic index (SDI) was created for each location based on income per capita, educational attainment, and fertility. RESULTS: In 2015, there were an estimated 422.7 million cases of CVD (95% uncertainty interval: 415.53 to 427.87 million cases) and 17.92 million CVD deaths (95% uncertainty interval: 17.59 to 18.28 million CVD deaths). Declines in the age-standardized CVD death rate occurred between 1990 and 2015 in all high-income and some middle-income countries. Ischemic heart disease was the leading cause of CVD health lost globally, as well as in each world region, followed by stroke. As SDI increased beyond 0.25, the highest CVD mortality shifted from women to men. CVD mortality decreased sharply for both sexes in countries with an SDI >0.75. CONCLUSIONS: CVDs remain a major cause of health loss for all regions of the world. Sociodemographic change over the past 25 years has been associated with dramatic declines in CVD in regions with very high SDI, but only a gradual decrease or no change in most regions. Future updates of the GBD study can be used to guide policymakers who are focused on reducing the overall burden of noncommunicable disease and achieving specific global health targets for CVD.

Environmental health · Intensive care medicine · Cardiac Health and Mental Health · Cardiovascular Health and Risk Factors · Diabetes, Cardiovascular Risks, and Lipoproteins · Medicine