Effect of Covid-19 Pandemic on the Change in Skeletal Muscle Mass in Older Patients with Type 2 Diabetes

A Retrospective Cohort Study

Bibliographic Data

ID15515930
AuthorsYuka Hasegawa (0000-0003-3435-6868, Kyoto Prefectural University of Medicine), Fuyuko Takahashi (0000-0002-2386-6953, Kyoto Prefectural University of Medicine), Yoshitaka Hashimoto (0000-0002-8794-0550, Kyoto Prefectural University of Medicine, corresponding author), Chihiro Munekawa (0000-0001-9603-1802, Kyoto Prefectural University of Medicine), Yukako Hosomi (Kyoto Prefectural University of Medicine), Takuro Okamura (0000-0001-7269-1697, Kyoto Prefectural University of Medicine), Hiroshi Okada (0000-0002-1707-970X, Kyoto Prefectural University of Medicine), Takafumi Senmaru (0000-0001-5883-0216, Kyoto Prefectural University of Medicine), Naoko Nakanishi (0000-0003-0092-2593, Kyoto Prefectural University of Medicine), Saori Majima (Kyoto Prefectural University of Medicine), Emi Ushigome (0000-0003-1031-4380, Kyoto Prefectural University of Medicine), Masahide Hamaguchi (0000-0002-8651-4445, Kyoto Prefectural University of Medicine), Masahiro Yamazaki (0000-0001-6293-3525, Kyoto Prefectural University of Medicine), Michiaki Fukui (0000-0003-0903-1797, Kyoto Prefectural University of Medicine)
Year2021
Volume18
Issue8
Pages4188-4188
Publication date2021-04-15
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph18084188
PMID33920957
OpenAlexW3156474633
LanguageEN
Citations received1
References cited55

Background : The aim of this study was to investigate the effect of the coronavirus disease (COVID-19) pandemic restrictions on the change in muscle mass in older patients with type 2 diabetes (T2D), who were not infected with COVID-19. Methods: In this retrospective cohort study, data were obtained from outpatients who underwent bioelectrical impedance analysis at least twice before April 2020 and at least once thereafter. Skeletal muscle mass index (SMI, kg/m 2 ) was calculated as appendicular muscle mass (kg) divided by height squared (m 2 ). Change in SMI (kg/m 2 /year) was calculated as (follow-up SMI-baseline SMI/follow-up period). The differences between the changes in SMI before and after the start of the COVID-19 pandemic were evaluated using paired t test. Results: This study recruited 56 patients, with a mean (SD) age of 75.2 (7.1) years. SMI changed from 6.7 (0.9) to 6.8 (0.9) kg/m 2 before the COVID-19 pandemic, whereas SMI changed from 6.8 (0.9) to 6.6 (0.9) kg/m 2 after the start of the COVID-19 pandemic. SMI decreased after the start of the COVID-19 pandemic compared with before the pandemic (-0.117 (0.240) vs. 0.005 (0.289) kg/m 2 /year, p = 0.049). This decrease was observed in men (-0.159 (0.257) vs. 0.031 (0.325) kg/m 2 /year, p = 0.038), patients with poor glycemic control (-0.170 (0.264) vs. 0.031 (0.285) kg/m 2 /year, p = 0.042), and those with a long diabetes duration (-0.153 (0.229) vs. 0.082 (0.291) kg/m 2 , p = 0.049). Conclusions: The COVID-19 pandemic restrictions caused muscle mass loss in older patents with T2D. Actions, including recommendation of exercise and adequate diet intake, are needed to prevent loss of muscle mass

Body mass index · Cohort · Cohort study · Coronavirus disease 2019 (COVID-19 · Diabetes mellitus · Disease · Glycemic · Pandemic · Retrospective cohort study · Type 2 diabetes · COVID-19 Clinical Research Studies · Long-Term Effects of COVID-19 · Medicine · Nutrition and Health in Aging · Endocrinology · Internal Medicine

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