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The brain in chronic insomnia and anxiety disorder

A combined structural and functional fMRI study

Bibliographic Data

ID15517614
AuthorsMinghe Xu (Jinzhou Medical University), Bo Li (0000-0002-7801-0319, People's Liberation Army 401 Hospital), Shuang Wang (0000-0002-7914-2081, Jinzhou Medical University), Chunlian Chen (Jinzhou Medical University), Zhe Liu (0000-0003-2983-3471, People's Liberation Army 401 Hospital), Yuqing Ji (0000-0002-3442-3349, People's Liberation Army 401 Hospital), Kai Liu (0000-0002-7995-6456, People's Liberation Army 401 Hospital, corresponding author), Yujun Niu (Jinzhou Medical University, corresponding author)
Year2024
Volume15
Pages1364713-1364713
Publication date2024-06-04
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2024.1364713
PMID38895035
OpenAlexW4399331524
LanguageEN
References cited59

The intensity of insomnia in patients was strongly related to the severity of anxiety. The lower GMV in the cerebellum could be interpreted as an imaging characteristic of CID. Reduced GMV in the insula, as well as aberrant function in the cingulate gyrus and prefrontal lobe, may contribute to the pathophysiology of CID and GAD. Abnormal function in the postcentral gyrus and angular gyrus may be associated with patients' clinical complaints

Anxiety · Cerebellum · Functional magnetic resonance imaging · Generalized anxiety disorder · Gyrus · Insula · Limbic lobe · Magnetic resonance imaging · Postcentral gyrus · Precentral gyrus · Psychiatry · Radiology · Superior frontal gyrus · Voxel-based morphometry · White matter · Functional Brain Connectivity Studies · Medicine · Neuroscience · Psychology · Sleep and related disorders · Sleep and Wakefulness Research

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