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Exploring Influences on Theory of Mind Impairment in Opioid Dependent Patients

Bibliographic Data

ID15519235
AuthorsKatharina Eidenmueller (Central Institute of Mental Health, corresponding author), Franz Grimm (Central Institute of Mental Health), Derik Hermann (0000-0003-4434-1221), Ulrich Frischknecht (0000-0003-1187-1867, Central Institute of Mental Health), Christiane Montag (0000-0002-3307-276X, Charité - Universitätsmedizin Berlin), Isabel Dziobek (0000-0003-0150-5353, Humboldt-Universität zu Berlin), Falk Kiefer (0000-0001-7213-0398, Central Institute of Mental Health), Nina Kim Bekier (0009-0004-9662-7242, Central Institute of Mental Health)
Year2021
Volume12
Pages721690-721690
Publication date2021-11-23
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2021.721690
PMID34887783
OpenAlexW3215937635
LanguageEN
Citations received2
References cited74

Theory of mind (ToM) is an aspect of social cognition impaired in different addictive disorders, including opioid addiction. This study aimed at replicating ToM deficits in opioid dependent patients undergoing opioid maintenance treatment (OMT) and exploring the influence of substance use related variables, executive functions and childhood maltreatment on ToM in opioid dependent patients. 66 opioid dependent patients were tested using the Movie for Assessment of Social Cognition (MASC) and compared with the data of healthy controls. Furthermore, the opioid dependent patients underwent testing for executive functions and filled in the Childhood Trauma Questionnaire (CTQ). Performance on the MASC was significantly poorer in the opioid dependence group than in the control group, even when recent additional drug use and psychiatric comorbidities were controlled for. No correlations were found between ToM and substance use related factors. Aspects of ToM performance in opioid dependent patients correlated significantly with different EF domains. ToM correlated significantly with the CTQ scales for physical maltreatment. The results confirm impaired ToM in opioid dependent patients and highlight executive functions and childhood maltreatment as influential factors. The lack of associations between ToM and substance use related variables and the association with childhood maltreatment suggest that ToM impairments might be a risk factor predating substance abuse

Addiction · Cognition · CTQ tree · Executive functions · Injury prevention · Opioid · Opioid addiction · Poison control · Psychiatry · Substance abuse · Substance dependence · Theory of mind · Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes · Child and Adolescent Psychosocial and Emotional Development · Clinical Psychology · Medicine · Neuroendocrine regulation and behavior · Psychology · Internal Medicine

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Unique citing works2
Citations per year0,5
Citation span2022 - 2023 (2)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 2

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