Changes in neurobiological markers of reactivity to alcohol-related stimuli in alcohol-dependent patients after two years of treatment

Bibliographic Data

ID15519906
AuthorsGabriel Rubio (0000-0002-1171-1508, Hospital Universitario 12 De Octubre, corresponding author), Marta Marín (Universidad Complutense de Madrid), Cristina Martín-Arriscado Arroba, Cristina Martín‐Arriscado Arroba (0000-0002-2147-2811, Research Institute Hospital 12 de Octubre), Enrique Rubio-Escobar (0009-0006-4708-4100, Research Institute Hospital 12 de Octubre), F Árias (0000-0003-0740-9282, Hospital Universitario 12 De Octubre), Abraham B Torregrosa (0009-0004-3438-9162, Instituto de Salud Carlos III), Daniela Navarro (0000-0002-3910-3993), Jorge Manzanares (0000-0002-4681-1533, Instituto de Neurociencias)
Year2025
Volume16
Pages1613169-1613169
Publication date2025-06-18
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2025.1613169
PMID40606822
OpenAlexW4411419384
LanguageEN
Citations received1
References cited68

The absence of changes in these neurobiological markers confirms the chronicity of moderate-severe AUD and the risk of relapse despite the end of treatment. These findings question the duration of alcohol dependence approaches and suggest the need to look for longer-term intervention alternatives

Addiction · Alcohol · Alcohol dependence · Alternative medicine · Biology · Craving · Cue reactivity · Pathology · Psychiatry · Reactivity (psychology · Clinical Psychology · Medicine · Memory and Neural Mechanisms · Mental Health Research Topics · Neuroscience · Neurotransmitter Receptor Influence on Behavior · Psychology

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