Antipsychotics lower peripheral markers of inflammation in drug-naïve early psychosis

A pilot study

Bibliographic Data

ID15523695
AuthorsNicole Šafářová (Charles University, corresponding author), Marián Kolenič (0000-0002-2382-3478, Charles University), Ivana Tašková (Charles University), Václav Čapek (0000-0002-8574-7001, Institute of Mental Health), Petra Fürstová (0000-0003-2377-1388, Institute of Mental Health), Filip Španiel (0000-0003-3479-696X, Charles University)
Year2026
Volume17
Pages1769162-1769162
Publication date2026-02-17
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2026.1769162
PMID41783735
OpenAlexW7129707096
LanguageEN
References cited50

These findings suggest a consistent dose-dependent anti-inflammatory effect during early antipsychotic treatment in FEP. Given the exploratory nature of this study, larger studies are needed to confirm these findings

Antipsychotic · Chlorpromazine · Clozapine · Inflammation · Pathophysiology · Peripheral · Psychosis · Schizophrenia (object-oriented programming · Inflammatory Biomarkers in Disease Prognosis · Schizophrenia research and treatment · Tryptophan and brain disorders

Tools

Open DOIOpen Access