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Aberrant Functional Connectivity of the Orbitofrontal Cortex Is Associated With Excited Symptoms in First-Episode Drug-Naïve Patients With Schizophrenia

Bibliographic Data

ID15524261
AuthorsCong‐Xin Chen (Nanjing Brain Hospital), Congxin Chen, Jingjing Yao (0000-0003-1404-7486, Honghu People’s Hospital), Yiding Lv (Nanjing Medical University), Xiaoxin Zhao (0000-0002-8610-3603, Shanghai Mental Health Center), Xinyue Zhang (0009-0009-4555-8650, Shenzhen KangNing Hospital), Jiaxi Lei, Yuan Li (0000-0001-7139-4391, Nanjing Brain Hospital, corresponding author), Yuxiu Sui (0000-0002-9364-4686, Nanjing Medical University, corresponding author)
Year2022
Volume13
Pages922272-922272
Publication date2022-07-28
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2022.922272
PMID35966466
OpenAlexW4288080583
LanguageEN
References cited73

Our results indicated the important role of the left orbitofrontal cortex in first-episode drug-naïve patients with SZ and suggested that the abnormal spontaneous activity of the orbitofrontal cortex may be valuable to predict the occurrence of excited symptoms. These results may provide a new direction to explore the excited symptoms of SZ

Cognition · Drug · Drug-naïve · Functional connectivity · Orbitofrontal cortex · Prefrontal cortex · Psychiatry · Schizophrenia (object-oriented programming · Clinical Psychology · Functional Brain Connectivity Studies · Medicine · Neural and Behavioral Psychology Studies · Neural dynamics and brain function · Neuroscience · Psychology

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