Obstructive sleep apnea and 19 gastrointestinal diseases

A Mendelian randomization study

Bibliographic Data

ID15524972
AuthorsWeiheng Yan (0000-0001-6732-2985, Chinese Academy of Medical Sciences & Peking Union Medical College), Jiayi Zhou (0000-0003-1173-3114, Children's Hospital of Capital Institute of Pediatrics), Miaomiao Jiang (0000-0002-4737-7564, Peking University Sixth Hospital), Yaru Kong (Chinese Academy of Medical Sciences & Peking Union Medical College), Han Qin (0000-0003-3786-3910, Children's Hospital of Capital Institute of Pediatrics), Yuwei Qi (0000-0001-7983-1971, Children's Hospital of Capital Institute of Pediatrics), Shan Wang (0000-0002-9487-0829, Capital Institute of Pediatrics, corresponding author), Jun Tai (0000-0003-3672-0125, Chinese Academy of Medical Sciences & Peking Union Medical College, corresponding author)
Year2024
Volume15
Pages1256116-1256116
Publication date2024-07-26
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2024.1256116
PMID39132315
OpenAlexW4401038171
LanguageEN
Citations received1
References cited72

This MR analysis provides compelling evidence of an independent causal relationship between genetically predicted OSA and an elevated risk of inflammation-related GDs. Besides, no causal association was observed between OSA and cancers. Further studies should be carried out to verify our findings

Bioinformatics · Biology · Disease · Gastrointestinal disease · Gene · Genetic variants · Genotype · Intensive care medicine · Mendelian randomization · Obstructive sleep apnea · Sleep (system call · Sleep apnea · Gastroesophageal reflux and treatments · Medicine · Obstructive Sleep Apnea Research · Tracheal and airway disorders · Gastroenterology · Genetics · Internal Medicine

Tools

Open DOIOpen Access