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Probable Autoimmune Depression in a Patient With Multiple Sclerosis and Antineuronal Antibodies

Bibliographic Data

ID15525282
AuthorsDominique Endres (0000-0001-7322-1195, University Medical Center Freiburg, corresponding author), Sebastian Rauer (0000-0002-9889-078X, University of Freiburg), Nils Venhoff (0000-0001-7729-2759, University Medical Center Freiburg), Patrick Süß (0000-0001-6926-1813, Universitätsklinikum Erlangen), Rick Dersch (0000-0002-7366-4401, University of Freiburg), Kimon Runge (0000-0002-0263-4360, University of Freiburg), Bernd L Fiebich (0000-0002-9261-6771, University of Freiburg), Kathrin Nickel (0000-0001-9863-317X, University Medical Center Freiburg), Miriam Matysik (University Medical Center Freiburg), Simon Maier (0000-0002-4285-8174, University of Freiburg), Katharina Domschke (0000-0002-2550-9132, University of Freiburg), Karl Egger (0000-0002-7753-4815, University of Freiburg), Harald Prüß (0000-0002-8283-7976, Charité - Universitätsmedizin Berlin), Ludger Tebartz van Elst (0000-0002-2274-5447, University Medical Center Freiburg)
Year2020
Volume11
Pages745-745
Publication date2020-08-13
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2020.00745
PMID32922313
OpenAlexW3049191015
LanguageEN
References cited18

The present patient suffered from a probable "autoimmune depression" in the context of newly diagnosed multiple sclerosis with typical MRI and CSF pathologies, alongside mild concomitant latent systemic autoimmune process (with high-titer ANAs and lymphopenia) and unknown antineuronal antibodies. The case report illustrates that a depressive syndrome suggestive of primary idiopathic depressive disorder may be associated with an autoimmune brain involvement. The detection of such organic affective disorders is of high clinical relevance for affected patients, as it enables alternative and more causal treatment approaches

Context (archaeology · Corpus callosum · Multiple sclerosis · Neuromyelitis Optica · Pathology · Autoimmune Neurological Disorders and Treatments · Medicine · Multiple Sclerosis Research Studies · Peripheral Neuropathies and Disorders · Immunology

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    Open Access•Eva Lüngen, Eva M Lüngen et al.•Frontiers in Psychiatry•2019

Citation velocityhistorical
Highly citedNo

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