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Associations between suicide attempts and clinical, metabolic, and inflammatory markers in Chinese patients with long-term schizophrenia

Bibliographic Data

ID15525840
AuthorsLili Zhao (0000-0002-6366-8206, Fourth Affiliated Hospital of Anhui Medical University), Lewei Liu (Anhui Medical University), Xu Zhang (0000-0003-3490-2216, Anhui Medical University), Xi Zhang (0009-0004-8281-1030, Anhui Mental Health Center), Xianhu Yao (Anshan Hospital), Wenzheng Li (0000-0003-2895-5434, Fourth Affiliated Hospital of Anhui Medical University), Lei Xia (0000-0001-7726-968X, Fourth Affiliated Hospital of Anhui Medical University, corresponding author), Huanzhong Liu (0000-0002-6774-3998, Anhui Medical University, corresponding author)
Year2025
Volume16
Pages1651246-1651246
Publication date2025-09-16
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2025.1651246
PMID41035953
OpenAlexW4414254099
LanguageEN
References cited57

Female gender, greater depressive severity, and elevated metabolic and proinflammatory markers (specifically TC and IL-1β) were independently associated with increased risk of SA in Chinese patients with long-term SCZ. These findings suggest that future interventions targeting metabolic and inflammatory pathways may hold promise for preventing SA in this population

Context (archaeology · Depression (economics · Inflammation · Major depressive disorder · Proinflammatory cytokine · Psychological intervention · Schizophrenia (object-oriented programming · Suicide Risk · Bipolar Disorder and Treatment · Stress Responses and Cortisol · Tryptophan and brain disorders

  • The role of inflammation in depression

    Open Access•Abraham H Miller, Andrew H Miller et al.•Nature Reviews Immunology•2016

  • Gender and Emotion Expression

    Open Access•Tara M Chaplin•Emotion Review•2015

  • Validation of the Insomnia Severity Index as an outcome measure for insomnia research

    Open Access•Célyne Bastien•Sleep Medicine•2001

  • The Positive and Negative Syndrome Scale (PANSS) for Schizophrenia

    Stanley R Kay, Abraham Fiszbein et al.•Schizophrenia Bulletin•1987

Citation velocityhistorical
Highly citedNo

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