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Interventions for opioid use disorder during pregnancy

A scoping review

Bibliographic Data

ID15526375
AuthorsAmanda L Elmore (0000-0003-3316-2797, University of South Florida, corresponding author), Matt Richey (University of South Florida), Dewan S Tahsin (University of South Florida), Gabriella Hinks (University of South Florida), William Velez-Jimenez (University of South Florida), Allison M Howard (0000-0003-1542-3893, University of South Florida), Tanner Wright (University of South Florida), Anthony Kendle (0000-0003-2647-9294, University of South Florida), Cheryl Vamos (University of South Florida)
Year2026
Volume17
Publication date2026-04-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2026.1770262
OpenAlexW7147701317
LanguageEN
References cited9

Background Opioid use disorder during pregnancy (OUD) continues to pose a significant public health challenge, requiring well-designed interventions. This scoping review identifies effective prenatal OUD interventions to promote the use of evidence-based approaches, such as medication for opioid use disorder (MOUD), and inform future research and clinical practice. Methods We searched PubMed, Embase, CINAHL, Scopus, and Web of Science for interventions for OUD during pregnancy from 2013 to 2023. Exclusions were non-English studies, animal research, non-prenatal interventions, pharmacological trials, and studies outside the U.S. Data were extracted on intervention context, sample, study aims, and results. We categorized each intervention by the socioecological model (SEM) level of implementation and applied the RE-AIM framework to evaluate reach, effectiveness, adoption, implementation, and maintenance. Results After review of 1,381 articles, a total of 31 intervention studies were included. Fourteen studies (45%) included over 75% non-Hispanic white participants. Seventeen studies (55%) were conducted at the individual level, six (19%) at the interpersonal level, and eight (26%) at the society/community level. Individual-level interventions focused on coordinated clinical care models, detoxification/tapering from (MOUD), and prenatal education. Interpersonal interventions included clinician education and group therapy. Community-level interventions targeted regional coordination of services, while society level studies examined the impact of policy change on MOUD access. Conclusion We identified a wide range of prenatal OUD interventions with varying approaches and summarized each by SEM implementation level. While MOUD access remains crucial, community-based interventions that address broader social determinants, and societal barriers may have the greatest impact in improving maternal health outcomes. Systematic Review Registration https://osf.io/ , identifier 10.17605/OSF.IO/8ZUAB

Interpersonal communication · Intervention (counseling · MEDLINE · Opioid use disorder · Pregnancy · Prenatal care · Psychological intervention · Public health · Opioid Use Disorder Treatment · Prenatal Substance Exposure Effects · Reproductive Health and Contraception

  • Steps for Conducting a Scoping Review

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  • RE-AIM Planning and Evaluation Framework

    Open Access•Russell E Glasgow, Samantha M Harden et al.•Frontiers in Public Health•2019

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    Open Access•Sarah Tabi, Sarah A Heitner et al.•Frontiers in Psychiatry•2020

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    Mary Peeler, Munish Gupta et al.•American Journal of Public Health•2020

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