Schizophrenia Associated with Epileptiform Discharges without Seizures Successfully Treated with Levetiracetam
Bibliographic Data
| ID | 15526701 |
|---|---|
| Authors | Dominique Endres (0000-0001-7322-1195, University of Freiburg), Evgeniy Perlov (0000-0002-5714-5441, University of Freiburg), Bernd Feige (0000-0002-9436-1258, University of Freiburg), Dirk‐Matthias Altenmüller (0000-0001-8610-2216, University of Freiburg), Dirk-Matthias Altenmüller, Nils Venhoff (0000-0001-7729-2759, University of Freiburg), Ludger Tebartz van Elst (0000-0002-2274-5447, University of Freiburg, corresponding author) |
| Year | 2017 |
| Volume | 8 |
| Pages | 12-12 |
| Publication date | 2017-02-08 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Psychiatry (JOURNAL) |
| Journal identifiers | ISSN: 1664-0640 • E-ISSN: 1664-0640 |
| Publisher | Frontiers Media (PUBLISHER • CH) |
| DOI | 10.3389/fpsyt.2017.00012 |
| PMID | 28228737 |
| OpenAlex | W2587613932 |
| Language | EN |
| Citations received | 2 |
| References cited | 21 |
The schizophrenia-like symptoms associated with epileptiform discharges but not overt seizures and the good response to antiepileptic treatment could be interpreted in the context of a (para)epileptic pathomechanism. The EEG alterations might be due to a polygenetic effect due to different genes. Mild immunological mechanisms in the framework of ulcerative colitis and increased ANA titers might have supported the network instability. This case report illustrates (1) the importance of EEG screenings in schizophrenia, (2) a potential pathogenetic role of epileptiform discharges in a subgroup of patients with schizophrenia-like symptoms, and (3) that antiepileptic medication with levetiracetam could be a successful treatment alternative in schizophrenia-like disorders with EEG alterations
Context (archaeology · Electroencephalography · Epilepsy · Levetiracetam · Paranoid schizophrenia · Psychiatry · Psychosis · Schizophrenia (object-oriented programming · Medicine · Obsessive-Compulsive Spectrum Disorders · Psychology · Schizophrenia research and treatment · Tryptophan and brain disorders · Pediatrics
| Unique citing works | 2 |
|---|---|
| Citations per year | 0,25 |
| Citation span | 2018 - 2019 (2) |
| Citation velocity | historical |
| Highly cited | No |
| Citation types | Neutral: 2 |