Dysregulated Methylation Patterns in Exon IV of the Brain-Derived Neurotrophic Factor (BDNF) Gene in Nicotine Dependence and Changes in BDNF Plasma Levels During Smoking Cessation
Bibliographic Data
Our findings replicate the findings of previous studies that BDNF plasma levels are altered in smokers. Furthermore, BDNF expression and gene methylation are altered during the first 14 days of cessation. Our novel findings of dysregulated methylation patterns in exon IV of the BDNF gene further support the thesis that BDNF plays a role in nicotine dependence
Biology · Brain-derived neurotrophic factor · DNA methylation · Epigenetics · Exon · Gene · Gene expression · Methylation · Neurotrophic factors · Nicotine · Nicotine withdrawal · Pathology · Receptor · Smoking cessation · Tropomyosin receptor kinase B · Autism Spectrum Disorder Research · Medicine · Nerve injury and regeneration · Neurogenesis and neuroplasticity mechanisms · Endocrinology · Genetics · Internal Medicine
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