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Caudate gray matter volumes and risk of relapse in Type A alcohol-dependent patients

A 7-year MRI follow-up study

Bibliographic Data

ID15528801
AuthorsCatherine Martelli (0000-0001-9797-1548, Université Paris-Saclay, corresponding author), Eric Artiges (0000-0003-4461-7646, Centre National de la Recherche Scientifique), Rubén Miranda (0000-0002-5816-4417, Hôpital Paul-Brousse), Bruno Roméo (0000-0003-3699-2024, Assistance Publique – Hôpitaux de Paris), Amélie Petillion (Assistance Publique – Hôpitaux de Paris), Henri‐Jean Aubin (0000-0002-6604-6672, Assistance Publique – Hôpitaux de Paris), Ammar Amirouche (Université Paris-Saclay), Sandra Chanraud (0000-0002-4299-3050, Université Paris Sciences et Lettres), Amine Benyamina (0000-0002-3679-1858, Hôpital Paul-Brousse), Jean-Luc Martinot (0000-0002-0136-0388, Université Paris-Saclay)
Year2023
Volume14
Pages1067326-1067326
Publication date2023-02-15
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2023.1067326
PMID36873223
OpenAlexW4320920492
LanguageEN
References cited12

Overall, the present investigation revealed larger caudate nuclei in the relapser AUD patient group both at baseline and at follow-up in the cross-sectional analyses. This finding suggest that a higher caudate volume could be a candidate risk factor of relapse. In patients with specific type A alcohol-dependence, we showed that long-term recovery in fronto-striato-limbic GM and WM volumes occurs during long-term abstinence. These results support the crucial role of frontal circuitry in AUD

Abstinence · Brain size · Caudate nucleus · Corpus callosum · Magnetic resonance imaging · Psychiatry · Radiology · Voxel-based morphometry · White matter · Advanced Neuroimaging Techniques and Applications · Medicine · Neurological and metabolic disorders · Neuroscience · Parkinson's Disease Mechanisms and Treatments · Psychology · Internal Medicine

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