Thyroid dysfunction in elderly first-episode drug-naïve major depressive disorder patients with comorbid dyslipidemia

Prevalence, clinical profile and associated factors

Bibliographic Data

ID15529682
AuthorsXiuhua Song (Qingdao Mental Health Center), Lei Yi (0000-0001-6388-0074, Qingdao Mental Health Center), Shenghai Wang (0000-0002-6539-4317, Qingdao Mental Health Center), Xiangyang Zhang (0000-0003-3326-382X, Anhui Medical University, corresponding author)
Year2026
Volume16
Pages1742901-1742901
Publication date2026-01-12
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2025.1742901
PMID41601507
OpenAlexW7123174819
LanguageEN
References cited40

Abnormal thyroid function is highly prevalent in elderly FEDN MDD patients with ALM; clinical severity, glucose, and lipid levels contribute to this comorbidity. These findings suggest that elderly, first-episode MDD patients with dyslipidemia, particularly those with elevated BMI, high blood glucose, and severe depressive symptoms, should undergo routine screening for thyroid dysfunction to facilitate early intervention

Depression (economics · Major depressive disorder · Thyroid · Thyroid disorder · Thyroid dysfunction · Thyroid function · Stress Responses and Cortisol · Thyroid Disorders and Treatments · Tryptophan and brain disorders

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