Children neuropsychological and behavioral scale-revision 2016 in the early detection of autism spectrum disorder

Bibliographic Data

ID15529704
AuthorsShu‐Ling Chen (0000-0002-1513-4365, Huazhong University of Science and Technology), Jinzhu Zhao (Tongji Hospital), Xiaolin Hu (0000-0003-0055-7290, Tongji Hospital), Lina Tang (0000-0001-7975-2472, Tongji Hospital), Jinhui Li (0000-0002-9823-8038, Tongji Hospital), Dandan Wu (0009-0008-5024-5141, Huazhong University of Science and Technology), Yan Tian (0000-0002-1286-1233, Tongji Hospital), Xu Lu (0000-0002-5630-0235, Tongji Hospital), Min Chen (0000-0001-8922-8789, Tongji Hospital), Shan Huang (0000-0002-8065-1596, Tongji Hospital), Yan Hao (0000-0001-8830-8189, Huazhong University of Science and Technology, corresponding author)
Year2022
Volume13
Publication date2022-07-22
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2022.893226
OpenAlexW4286486509
LanguageEN
Citations received3
References cited9

Background The Children Neuropsychological and Behavioral Scale-Revision 2016 (CNBS-R2016) is a widely used developmental assessment tool for children aged 0–6 years in China. The communication warning behavior subscale of CNBS-R2016 is used to assess the symptoms of autism spectrum disorder (ASD), and its value of >30 points indicates ASD based on CNBS-R2016. However, we observed that children with relatively lower values were also diagnosed with ASD later on in clinical practice. Thus, this study aimed to identify the suitable cutoff value for ASD screening recommended by the communication warning behavior of CNBS-R2016. Materials and methods A total of 90 typically developing (TD) children and 316 children with developmental disorders such as ASD, developmental language disorder (DLD), and global developmental delay (GDD; 130 in the ASD group, 100 in the DLD group, and 86 in the GDD group) were enrolled in this study. All subjects were evaluated based on the CNBS-R2016. The newly recommended cutoff value of communication warning behavior for screening ASD was analyzed with receiver operating curves. Results Children in the ASD group presented with lower developmental levels than TD, DLD, and GDD groups in overall developmental quotient assessed by CNBS-R2016. We compared the consistency between the scores of communication warning behavior subscale and Autism Behavior Checklist (ABC), Childhood Autism Rating Scale (CARS), Autism Diagnostic Observation Schedule, second edition (ADOS-2), and clinical diagnosis for the classification of ASD at a value of 30 based on the previously and newly recommended cutoff value of 12 by the CNBS-R2016. The Kappa values between the communication warning behavior and ABC, CARS, ADOS-2, and clinical diagnosis were 0.494, 0.476, 0.137, and 0.529, respectively, with an agreement rate of 76.90%, 76.26%, 52.03%, and 82.27%, respectively, when the cutoff point was 30. The corresponding Kappa values were 0.891, 0.816, 0.613, and 0.844, respectively, and the corresponding agreement rate was 94.62%, 90.82%, 90.54%, and 93.10%, respectively, when the cutoff point was 12. Conclusion The communication warning behavior subscale of CNBS-R2016 is important for screening ASD. When the communication warning behavior score is 12 points or greater, considerable attention and further comprehensive diagnostic evaluation for ASD are required to achieve the early detection and diagnosis of ASD in children

Autism · Autism Diagnostic Observation Schedule · Autism spectrum disorder · Childhood Autism Rating Scale · Cognition · Developmental psychology · Neuropsychology · Pervasive developmental disorder · Psychiatry · Rating scale · Autism Spectrum Disorder Research · Child Development and Digital Technology · Clinical Psychology · Genetics and Neurodevelopmental Disorders · Medicine · Psychology · Pediatrics

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