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Association of Cerebral Artery Stenosis With Post-stroke Depression at Discharge and 3 Months After Ischemic Stroke Onset

Bibliographic Data

ID15529798
AuthorsXiuli Qiu (0000-0002-3211-1253, Tongji Hospital), Jinfeng Miao (0000-0001-6229-3767, Tongji Hospital), Yan Lan (Huazhong University of Science and Technology), Wenzhe Sun (0000-0002-7305-8671, Huazhong University of Science and Technology), Yuxi Chen (0009-0009-4146-9036, Johns Hopkins University), Ziqin Cao (0000-0002-2465-5701, Emory University), Li Guo (0000-0003-3821-4058, Tongji Hospital), Xin Zhao (0000-0002-6232-9835, Huazhong University of Science and Technology), Zhou Zhu (0000-0003-3324-483X, Tongji Hospital, corresponding author), Suiqiang Zhu (0000-0002-0421-3391, Huazhong University of Science and Technology, corresponding author)
Year2020
Volume11
Pages585201-585201
Publication date2020-11-25
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2020.585201
PMID33324257
OpenAlexW3110291533
LanguageEN
Citations received3
References cited3

Background: Post-stroke depression (PSD) is one of the most common complications after stroke, which seriously affects patients' recovery outcome. Although vascular depression has been extensively studied, the relationship between cerebral artery stenosis and PSD has not been clarified so far. Methods: Two hundred ninety-eight patients with ischemic stroke (72 women, 226 men) with computed tomography angiography (CTA) or magnetic resonance angiography (MRA) were included in this study. Cerebral artery stenosis ≥50% was used as the cut-off value. The DSM-V diagnostic criteria of PSD was met and the 17-item Hamilton Rating Scale for Depression (HAMD-17) score over 7 at discharge and 3 months after stroke onset was regarded as the primary outcome. The χ 2 -test, Mann-Whitney U -test, and t -test were used to check for statistical significance. Results: At discharge, Barthel index ( p p = 0.019), drinking history ( p = 0.048), basilar artery stenosis ( p = 0.037) were significantly associated with PSD. At 3 months after ischemic stroke onset, Barthel index ( p = 0.011), left middle cerebral artery stenosis ( p = 0.012), female gender ( p = 0.001) were significantly associated with PSD. Conclusions: The findings demonstrated that left middle cerebral artery and basilar artery stenosis are associated with PSD. It was suggested that cerebral artery stenosis was a risk factor of PSD and should be recognized and intervened early. Registration Number: ChiCTR-ROC-17013993

Basilar artery · Cardiology · Cerebral arteries · Depression (economics · Hamd · Ischemia · Magnetic resonance angiography · Magnetic resonance imaging · Middle cerebral artery · Post-stroke depression · Radiology · Stenosis · Stroke (engine · Acute Ischemic Stroke Management · Cerebrovascular and Carotid Artery Diseases · Medicine · Stroke Rehabilitation and Recovery · Internal Medicine

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Unique citing works3
Citations per year0,6
Citation span2021 - 2025 (5)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 3

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