Caracterización microbiológica y molecular de la resistencia antimicrobiana de Escherichia coli uropatógenas de hospitales públicos peruanos

Datos Bibliográficos

ID15533471
AutoresPool Marcos-Carbajal (0000-0002-7741-0337, Universidad Peruana Cayetano Heredia, autor de correspondencia), Guillermo Salvatierra (0000-0002-6887-2599, Universidad Peruana Cayetano Heredia), José Yareta-Yareta (0000-0002-8909-1724, Universidad Peruana Unión), Jimena Edith Pino-Dueñas (0000-0003-4563-5459, Ospedale Maggiore), Nancy Vásquez (0000-0001-7311-1244, Ospedale Maggiore), Pilar Elizabeth Diaz-Rengifo (0000-0002-0929-4602, Dirección Regional de Salud del Callao), Isabel de Miguel Martínez (0000-0002-5126-7480, Universidad Nacional de Tumbes), Percy Asmat (0000-0003-1899-4499, Private University of Trujillo), Percy Asmat-Marrufo (0000-0003-3377-6713), Carlos Peralta (0000-0002-9605-8324, Amazon National University of Madre de Dios), Caridad Huamani (0000-0002-6597-1671, Amazon National University of Madre de Dios), Alexander Briones (0000-0003-4849-6466, Universidad Particular de Iquitos), M M Mangas Ruiz (0000-0002-0902-8937, Hospital de Clínicas), Nicomedes Laura (Universidad Nacional de Huancavelica), Álvaro Luque (Universidad Andina Néstor Cáceres Velásquez), Leonel Arapa (University of Perugia), Pablo Tsukayama (0000-0002-1669-2553, Universidad Peruana Cayetano Heredia)
Año2021
Volumen38
Número1
Páginas119-23
Fecha de publicación2021-03-16
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaRevista Peruana de Medicina Experimental y Salud Pública (JOURNAL)
Identificadores de la revistaISSN: 1726-4634 • E-ISSN: 1726-4642
EditorialNational Institute of Health of Peru (PUBLISHER • PE)
DOI10.17843/rpmesp.2021.381.6182
PMID34190903
OpenAlexW3131883911
IdiomaES
Referencias citadas1

We characterized the antimicrobial resistance of 70 Escherichia coli isolates obtained from patients with a urinary tract infection (UTI) from 8 public hospitals in Peru. Resistance profiles were identified using the automated MicroScan® system. A standard polymerase chain reaction was used for the detection of the bla TEM, bla CTX-M, bla SHV and bla PER genes. The 65.7% (46/70) of the isolates presented a multidrug-resistant phenotype and 55.7% (39/70) were extended-spectrum beta-lactamases producers. High levels of resistance were detected for ampicillin (77,1%), ciprofloxacin (74,3%), trimethoprim/sulfamethoxazole (62,9%), cefepime (57,1%), and cefuroxime (57,1%). The bla TEM gene was the most frequent (31,4%), followed by bla CTX-M (18,6%) and bla SHV (2,9%) genes. These results show high resistance levels to antimicrobials of clinical use in E. coli isolates from hospital UTI patients in Peru

Antibiotic resistance · Antibiotics · Biology · Cefepime · Gynecology · Imipenem · Antibiotic Resistance in Bacteria · Gut microbiota and health · Medicine · Urinary Tract Infections Management · Microbiology