Case report
Liver failure as a debut of autoimmune hepatitis triggered by dengue virus in a pregnant woman
Bibliographic Data
| ID | 15533600 |
|---|---|
| Authors | Karina Sato‐Espinoza (0000-0002-1725-5865, Peruvian University of Applied Sciences, corresponding author), Diego Berrospi-Castillo (0000-0003-2327-8841, Universidad Peruana Cayetano Heredia), Javier Díaz‐Ferrer (0000-0001-9748-5005) |
| Year | 2024 |
| Volume | 41 |
| Issue | 2 |
| Pages | 209-13 |
| Publication date | 2024-06-21 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Revista Peruana de Medicina Experimental y Salud Pública (JOURNAL) |
| Journal identifiers | ISSN: 1726-4634 • E-ISSN: 1726-4642 |
| Publisher | National Institute of Health of Peru (PUBLISHER • PE) |
| DOI | 10.17843/rpmesp.2024.412.13485 |
| PMID | 39166644 |
| OpenAlex | W4399879760 |
| Language | EN |
| Citations received | 1 |
| References cited | 3 |
Autoimmune hepatitis (AIH) is a complex condition with unclear origins, involving genetic susceptibility and environmental triggers that lead to immune system dysfunction. We report a case of a pregnant woman from a mosquito-borne disease-endemic area who presented jaundice, abdominal pain, and pruritus, complicated by acute liver failure. Immunological markers showed AIH triggered by dengue virus infection, which was confirmed by a positive IgM test. Treatment with supportive care followed by steroids and azathioprine resulted in favorable outcomes, averting the need for a liver transplant. Although AIH can be triggered by viruses, the role of dengue in its pathogenesis remains poorly understood. Regular clinical monitoring is vital for managing AIH, particularly during pregnancy, due to variable immune status and treatment responses. Further research is necessary to understand the link between dengue infection and AIH. Individualized treatment strategies are crucial, especially during pregnancy, in order to ensure favorable outcomes
Autoimmune hepatitis · Azathioprine · Biology · Dengue fever · Dengue virus · Disease · Hepatitis · Immune system · Jaundice · Liver disease · Pregnancy · Hepatitis B Virus Studies · Hepatitis Viruses Studies and Epidemiology · Liver Diseases and Immunity · Medicine · Immunology · Internal Medicine
| Citations per year | 0.5 |
|---|---|
| Citation span | 2024 - 2024 (1) |
| Highly cited | No |