Considerations in developing lipid‐based nutrient supplements for prevention of undernutrition
Experience from the I nternational L ipid‐ B ased N utrient S upplements ( iLiNS ) P roject
Bibliographic Data
| ID | 15535814 |
|---|---|
| Authors | Mary Arimond (0000-0003-1357-9077, University of California, Davis, corresponding author), Mamane Zeilani (0000-0003-4566-6394, Nutriset S.A.S. Malaunay France), Svenja Jungjohann (0000-0002-8343-7843, Global Alliance for Improved Nutrition), Kendall H Brown (0000-0001-6498-3120, University of California, Davis), Per Ashorn (0000-0003-2311-2593, Tampere University of Applied Sciences), Lindsay H Allen (0000-0002-8729-5213, University of California, Davis), Kathryn G Dewey (0000-0002-4185-3451, University of California, Davis) |
| Year | 2013 |
| Volume | 11 |
| Issue | S4 |
| Pages | 31-61 |
| Publication date | 2013-05-06 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Maternal and Child Nutrition (JOURNAL) |
| Journal identifiers | ISSN: 1740-8695 • E-ISSN: 1740-8709 |
| Publisher | Wiley (PUBLISHER • GB) |
| DOI | 10.1111/mcn.12049 |
| PMID | 23647784 |
| OpenAlex | W2162194090 |
| Language | EN |
| Citations received | 45 |
| References cited | 87 |
The International Lipid-Based Nutrient Supplements (iLiNS) Project began in 2009 with the goal of contributing to the evidence base regarding the potential of lipid-based nutrient supplements (LNS) to prevent undernutrition in vulnerable populations. The first project objective was the development of acceptable LNS products for infants 6-24 months and for pregnant and lactating women, for use in studies in three countries (Burkina Faso, Ghana and Malawi). This paper shares the rationale for a series of decisions in supplement formulation and design, including those related to ration size, ingredients, nutrient content, safety and quality, and packaging. Most iLiNS supplements have a daily ration size of 20 g and are intended for home fortification of local diets. For infants, this ration size is designed to avoid displacement of breast milk and to allow for dietary diversity including any locally available and accessible nutrient-dense foods. Selection of ingredients depends on acceptability of flavour, micronutrient, anti-nutrient and essential fatty acid contents. The nutrient content of LNS designed to prevent undernutrition reflects the likelihood that in many resource-poor settings, diets of the most nutritionally vulnerable individuals (infants, young children, and pregnant and lactating women) are likely to be deficient in multiple micronutrients and, possibly, in essential fatty acids. During ingredient procurement and LNS production, safety and quality control procedures are required to prevent contamination with toxins or pathogens and to ensure that the product remains stable and palatable over time. Packaging design decisions must include consideration of product protection, stability, convenience and portion control
Biology · Breast milk · Environmental health · Malnutrition · Micronutrient · Nutraceutical · Nutrient · Breastfeeding Practices and Influences · Child Nutrition and Feeding Issues · Child Nutrition and Water Access · Medicine · Biotechnology · Ecology · Food Science
Independent and combined effects of improved water, sanitation, and hygiene, and improved complementary feeding, on child stunting and anaemia in rural Zimbabwe
Effect of prenatal multiple micronutrient supplements and medium-quantity lipid-based nutritional supplements on maternal weight gain and infant birth weight in rural Niger
Food-based approaches to improve nutritional quality of the complementary diet to address stunting
Impact of small‐quantity lipid‐based nutrient supplement on hemoglobin, iron status and biomarkers of inflammation in pregnant Ghanaian women
Dried small fish provide nutrient densities important for the first 1000 days
Comparison of methods to assess adherence to small‐quantity lipid‐based nutrient supplements ( SQ ‐ LNS ) and dispersible tablets among young B urkinabé children participating in a community‐based intervention trial
Local foods can meet micronutrient needs for women in urban Burkina Faso, but only if rarely consumed micronutrient‐dense foods are included in daily diets
Willingness to pay for small‐quantity lipid‐based nutrient supplements for women and children
The impact of integrated prevention and treatment on child malnutrition and health
Situation and determinants of the infant and young child feeding (Iycf) indicators in Madagascar
A cluster-randomized, controlled trial of nutritional supplementation and promotion of responsive parenting in Madagascar
Feeding practices and factors associated with the provision of iron-rich foods to children aged 6–23 months in Matam area, Senegal
Population-attributable risk estimates for factors associated with inappropriate complementary feeding practices in The Gambia
Provision of Lipid-Based Nutrient Supplements from Age 6 to 18 Months Does Not Affect Infant Development Scores in a Randomized Trial in Malawi
Unintended effects of a targeted maternal and child nutrition intervention on household expenditures, labor income, and the nutritional status of non-targeted siblings in Ghana
Acceptability of locally‐produced Ready‐to‐Use Supplementary Food (Rusf) for children under two years in Cambodia
Effect of a Behavioral Change Communication Strategy Coupled With Small‐Quantity Lipid‐Based or Micro‐Nutrient Supplements on Stunting and Obesity in Children in Baja Verapaz, Guatemala
Head Circumference Versus Length and Weight Deficits up to 2 Years of Age in Bangladesh
Effectiveness of a locally produced ready‐to‐use supplementary food in preventing growth faltering for children under 2 years in Cambodia
Associations of maternal nutrition during pregnancy and post‐partum with maternal cognition and caregiving
Prevalence of morbidity symptoms among pregnant and postpartum women receiving different nutrient supplements in Ghana and Malawi
Effects of lipid‐based nutrient supplements or multiple micronutrient supplements compared with iron and folic acid supplements during pregnancy on maternal haemoglobin and iron status
Supplementation during pregnancy with small‐quantity lipid‐based nutrient supplements or multiple micronutrients, compared with iron and folic acid, increases women's urinary iodine concentration in semiurban Ghana
Patterns and determinants of small‐quantity LNS utilization in rural Malawi and Mozambique
Impacts of an egg complementary feeding trial on energy intake and dietary diversity in Malawi
Maternal plasma cholesterol and duration of pregnancy
Formulation and acceptability of local nutrient‐dense foods for young children
Nutrient supplementation may adversely affect maternal oral health – a randomised controlled trial in rural M alawi
Newborn physical condition and breastfeeding behaviours
Impact of small quantity lipid‐based nutrient supplements on infant and young child feeding practices at 18 months of age
An integrated infant and young child feeding and small‐quantity lipid‐based nutrient supplementation programme in the Democratic Republic of Congo is associated with improvements in breastfeeding and handwashing behaviours but not dietary diversity
Provision of lipid‐based nutrient supplements to H onduran children increases their dietary macro‐ and micronutrient intake without displacing other foods
The impact of maternal diet fortification with lipid‐based nutrient supplements on postpartum depression in rural Malawi
Considerations in developing lipid‐based nutrient supplements for prevention of undernutrition
Consumption of multiple micronutrients or small-quantity lipid-based nutrient supplements containing iodine at the recommended dose during pregnancy, compared with iron and folic acid, does not affect women’s urinary iodine concentration in rural Malawi
The cost-effectiveness of small-quantity lipid-based nutrient supplements for prevention of child death and malnutrition and promotion of healthy development
The effect of providing lipid-based nutrient supplements on morbidity in rural Malawian infants and young children
Food insecurity, social and behaviour change and distribution model
Effects of lipid-based nutrient supplements v . micronutrient powders on nutritional and developmental outcomes among Peruvian infants
Small-quantity lipid-based nutrient supplements for children age 6–24 months
Preventive small-quantity lipid-based nutrient supplements reduce severe wasting and severe stunting among young children
Characteristics that modify the effect of small-quantity lipid-based nutrient supplementation on child growth
Characteristics that modify the effect of small-quantity lipid-based nutrient supplementation on child anemia and micronutrient status
Lipid-based nutrient supplements and all-cause mortality in children 6–24 months of age
Small-quantity lipid-based nutrient supplements for the prevention of child malnutrition and promotion of healthy development
Update on Technical issues concerning Complementary Feeding of Young Children in Developing Countries and Implications for Intervention Programs
The Epidemiology of Global Micronutrient Deficiencies
Simple Food Group Diversity Indicators Predict Micronutrient Adequacy of Women’s Diets in 5 Diverse, Resource-Poor Settings
Randomized comparison of 3 types of micronutrient supplements for home fortification of complementary foods in Ghana
Maternal and child undernutrition
Complementary feeding messages that target cultural barriers enhance both the use of lipid‐based nutrient supplements and underlying feeding practices to improve infant diets in rural Zimbabwe
Acceptability of lipid-based nutrient supplements (LNS) among Ghanaian infants and pregnant or lactating women
Acceptability of three novel lipid-based nutrient supplements among Malawian infants and their caregivers
Screening for anti‐nutritional compounds in complementary foods and food aid products for infants and young children
Use of lipid‐based nutrient supplements (LNS) to improve the nutrient adequacy of general food distribution rations for vulnerable sub‐groups in emergency settings
Supplementary feeding with fortified spread among moderately underweight 6–18‐month‐old rural Malawian children
Acceptability of zinc-fortified, lipid-based nutrient supplements (LNS) prepared for young children in Burkina Faso
Examination of facilitators and barriers to home‐based supplemental feeding with ready‐to‐use food for underweight children in western Uganda
Considerations in developing lipid‐based nutrient supplements for prevention of undernutrition
Formative research for the development of a market‐based home fortification programme for young children in Niger
Feeding patterns of underweight children in rural Malawi given supplementary fortified spread at home
Dietary intakes of women during pregnancy in low- and middle-income countries
An effectiveness trial showed lipid-based nutrient supplementation but not corn–soya blend offered a modest benefit in weight gain among 6- to 18-month-old underweight children in rural Malawi
Malawian mothers’ attitudes towards the use of two supplementary foods for moderately malnourished children
Intra-household use and acceptability of Ready-to-Use-Supplementary-Foods distributed in Niger between July and December 2010
Development of food variety in children
Feeding patterns and behaviors during home supplementation of underweight Malawian children with lipid-based nutrient supplements or corn-soy blend
| Unique citing works | 45 |
|---|---|
| Citations per year | 3,46 |
| Citation span | 2013 - 2025 (13) |
| Citation velocity | recent |
| Highly cited | No |
| Citation types | Neutral: 45 |