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Maximizing the benefits and minimizing the risks of intervention programs to address micronutrient malnutrition

Symposium report

Bibliographic Data

ID15535827
AuthorsMaaike J Bruins (0000-0001-9517-4617, DSM (Netherlands), corresponding author), Roland Kupka (0000-0002-7943-1705, United Nations Children's Fund), Michael Zimmermann (0000-0002-5797-3589, ETH Zurich), Georg Lietz (0000-0002-2103-0335, NIHR Newcastle Biomedical Research Centre), Reina Engle-Stone (0000-0003-2446-6166, University of California, Davis), K Kraemer (0000-0002-2592-6104, Sight and Life)
Year2016
Volume12
Issue4
Pages940-948
Publication date2016-08-09
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueMaternal and Child Nutrition (JOURNAL)
Journal identifiersISSN: 1740-8695 • E-ISSN: 1740-8709
PublisherWiley (PUBLISHER • GB)
DOI10.1111/mcn.12334
PMID27501994
OpenAlexW2511073323
LanguageEN
Citations received2
References cited4

Interventions to address micronutrient deficiencies have large potential to reduce the related disease and economic burden. However, the potential risks of excessive micronutrient intakes are often not well determined. During the Global Summit on Food Fortification, 9-11 September 2015, in Arusha, a symposium was organized on micronutrient risk-benefit assessments. Using case studies on folic acid, iodine and vitamin A, the presenters discussed how to maximize the benefits and minimize the risks of intervention programs to address micronutrient malnutrition. Pre-implementation assessment of dietary intake, and/or biomarkers of micronutrient exposure, status and morbidity/mortality is critical in identifying the population segments at risk of inadequate and excessive intake. Dietary intake models allow to predict the effect of micronutrient interventions and their combinations, e.g. fortified food and supplements, on the proportion of the population with intakes below adequate and above safe thresholds. Continuous monitoring of micronutrient intake and biomarkers is critical to identify whether the target population is actually reached, whether subgroups receive excessive amounts, and inform program adjustments. However, the relation between regular high intake and adverse health consequences is neither well understood for many micronutrients, nor do biomarkers exist that can detect them. More accurate and reliable biomarkers predictive of micronutrient exposure, status and function are needed to ensure effective and safe intake ranges for vulnerable population groups such as young children and pregnant women. Modelling tools that integrate information on program coverage, dietary intake distribution and biomarkers will further enable program makers to design effective, efficient and safe programs

Environmental health · Food fortification · Malnutrition · Micronutrient · Micronutrient deficiency · Pathology · Population · Psychological intervention · Child Nutrition and Water Access · Iron Metabolism and Disorders · Medicine · Nutrition and Health in Aging

  • Provision of low‐iron micronutrient powders on alternate days is associated with lower prevalence of anaemia, stunting, and improved motor milestone acquisition in the first year of life

    Open Access•Ashenafi Geletu, Azeb Lelisa et al.•Maternal and Child Nutrition•2019

  • Maximizing the benefits and minimizing the risks of intervention programs to address micronutrient malnutrition

    Open Access•Maaike J Bruins, Roland Kupka et al.•Maternal and Child Nutrition•2016

  • The Epidemiology of Global Micronutrient Deficiencies

    Open Access•Regan L Bailey, Keith P West et al.•Annals of Nutrition and Metabolism•2015

  • The Interaction between Nutrition and Infection

    Péter Katona, Judit Katona‐apte•Clinical Infectious Diseases•2008

  • Maternal and child undernutrition and overweight in low-income and middle-income countries

    Open Access•Robert E Black, Cesar G Victora et al.•The Lancet•2013

  • Maximizing the benefits and minimizing the risks of intervention programs to address micronutrient malnutrition

    Open Access•Maaike J Bruins, Roland Kupka et al.•Maternal and Child Nutrition•2016

Unique citing works2
Citations per year0,2
Citation span2016 - 2019 (4)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 2

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