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Innovative optimization of ready to use food for treatment of acute malnutrition

Bibliographic Data

ID15536771
AuthorsGaryk Brixi (0000-0002-1253-0522, Winston Churchill High School Potomac MD USA, corresponding author)
Year2018
Volume14
Issue4
Pagese12599-e12599
Publication date2018-03-14
Open AccessYes
TypeARTICLE
VenueMaternal and Child Nutrition (JOURNAL)
Journal identifiersISSN: 1740-8695 • E-ISSN: 1740-8709
PublisherWiley (PUBLISHER • GB)
DOI10.1111/mcn.12599
PMID29536665
OpenAlexW2791213121
LanguageEN
Citations received3
References cited19

Treatment of acute malnutrition typically requires the provision of ready-to-use food (RUF). Common RUF is effective but expensive, being manufactured from costly ingredients, and shipped worldwide from few global suppliers. I developed a linear programming tool to create RUF optimized for low cost using locally grown crops while maintaining necessary nutritional goals and other constraints. My tool utilizes a database of the nutritional value, price, and water efficiency of suitable ingredients and allows adjustment of constraints, including nutrients, flavour, and crop water efficiency. It is designed to (a) address nutrient requirements conforming to current standards and practice; (b) optimize RUF formulae for low cost using a wide range of ingredients for nutritional value and acceptability improvement; (c) ensure protein quality through protein digestibility corrected amino acid score; and (d) adjust RUF formulae according to locally grown crop selection, local prices, and crop water footprint. The tool creates formulae free of expensive dairy ingredients, ensuring desired protein digestibility corrected amino acid score by automatically balancing proteins with complementary quantities of essential amino acids. Using publicly available data with an application to Nigeria, my tool created RUF formulae suitable for local production using local crops to meet all nutrient requirements at a fraction of the ingredient cost and water footprint of current formulae, demonstrating the tool's effectiveness. Optimization of RUF for low cost using locally grown crops will facilitate local production and reduce ingredient as well as transport costs, so more patients can receive lifesaving treatment

Agricultural engineering · Footprint · Ingredient · Malnutrition · Nutrient · Production (economics · Quality (philosophy · Child Nutrition and Feeding Issues · Child Nutrition and Water Access · Engineering · Food Security and Health in Diverse Populations · Medicine · Biotechnology

  • Combating Malnutrition

    Open Access•Amina Sa’id Muhammad, Eridiong O Onyenweaku et al.•International Journal of…•2025

  • A Global Scoping Review on Alternative Ready‐to‐Use Therapeutic Foods

    Open Access•Patrizia Pajak, Sisay Mengist Beniyam Teshome et al.•Maternal and Child Nutrition•2025

  • Innovative optimization of ready to use food for treatment of acute malnutrition

    Open Access•Garyk Brixi•Maternal and Child Nutrition•2018

  • The green, blue and grey water footprint of crops and derived crop products

    Open Access•Mesfin M Mekonnen, Arjen Y Hoekstra•Hydrology and earth system sciences•2011

  • Local versus offshore production of ready‐to‐use therapeutic foods and small quantity lipid‐based nutrient supplements

    Open Access•Joel Segrè, Grace Liu et al.•Maternal and Child Nutrition•2016

  • Innovative optimization of ready to use food for treatment of acute malnutrition

    Open Access•Garyk Brixi•Maternal and Child Nutrition•2018

  • Effectiveness of milk whey protein‐based ready‐to‐use therapeutic food in treatment of severe acute malnutrition in M alawian under‐5 children

    Open Access•Paluku Bahwere, Theresa Banda et al.•Maternal and Child Nutrition•2014

  • Comparison of the effectiveness of a milk‐free soy‐maize‐sorghum‐based ready‐to‐use therapeutic food to standard ready‐to‐use therapeutic food with 25% milk in nutrition management of severely acutely malnourished Z ambian children

    Open Access•Abel Hailu Irena, Paluku Bahwere et al.•Maternal and Child Nutrition•2013

  • Development and acceptability of a novel milk‐free soybean–maize–sorghum ready‐to‐use therapeutic food (SMS‐Rutf) based on industrial extrusion cooking process

    Open Access•Victor O Owino, Victor Owino et al.•Maternal and Child Nutrition•2012

  • Contribution to the development of a food guide in Benin

    Open Access•Sarah Levesque, Hélène Delisle et al.•Public Health Nutrition•2015

Citations per year0.38
Citation span2018 - 2025 (8)
Highly citedNo

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