The High Seropositivity of Mumps Virus IgG Antibodies among School-Aged Children in Rural Areas of the Mbarali District in the Mbeya Region, Tanzania

It Is High Time for Consideration in the National Immunization Program

Bibliographic Data

ID15717446
AuthorsMariam M Mirambo (0000-0003-2313-3079, Catholic University of Health and Allied Sciences, corresponding author), Fausta Michael (0000-0003-2236-7420, Ministry of Health, Community Development, Gender, Elderly and Children), Helmut Nyawale (0000-0001-6916-6859, Catholic University of Health and Allied Sciences), Frank Mbugano (Catholic University of Health and Allied Sciences), Maneja B Walwa (Catholic University of Health and Allied Sciences), Dina Mahamba (The University of Dodoma), Delfina R Msanga (0000-0002-3472-9620, Catholic University of Health and Allied Sciences), Bernard Okamo (Catholic University of Health and Allied Sciences), Prisca Damiano (Catholic University of Health and Allied Sciences), Stephen E Mshana (0000-0002-7526-6271, Catholic University of Health and Allied Sciences)
Year2024
Volume11
Issue1
Pages73-73
Publication date2024-01-09
Open AccessYes
TypeARTICLE
VenueChildren (JOURNAL)
Journal identifiersISSN: 2227-9067 • E-ISSN: 2227-9067
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/children11010073
PMID38255386
OpenAlexW4390777626
LanguageEN
References cited27

Mumps is an acute contagious viral disease caused by paramyxovirus characterized by complications that include orchitis, oophoritis, aseptic meningitis, and spontaneous abortion among many others. This study reports high mumps IgG seropositivity among school-aged children in rural areas of the Mbeya region, information that might be useful in understanding the epidemiology of mumps and instituting appropriate control measures including vaccination. Between May and July 2023, a cross-sectional study involving 196 enrolled children aged 5-13 years was conducted. Sociodemographic information and other relevant information were collected using a structured data collection tool. Blood samples were collected and used to detect mumps immunoglobulin G antibodies using indirect enzyme-linked immunosorbent assay (ELISA). A descriptive analysis was performed using STATA version 15. The median age of the enrolled children was 13 (interquartile range (IQR): 8-13) years. The seropositivity of mumps IgG antibodies was 88.8% (174/196, 95% CI: 83.5-92.5). By multivariable logistic regression analysis, history of fever (OR: 5.36, 95% CI: 1.02-28.22, p = 0.047) and sharing utensils (OR: 8.05, 95% CI: 1.99-32.65, p = 0.003) independently predicted mumps IgG seropositivity. More than three-quarters of school-aged children in rural areas of the Mbeya region are mumps IgG-seropositive, which is significantly associated with the sharing of utensils and history of fever. This suggests that the virus is endemic in this region, which calls for further studies across the country so as to institute evidence-based, appropriate control measures including a vaccination program

Tanzania · Vaccination · Medicine · Respiratory viral infections research · Vaccine Coverage and Hesitancy · Virology and Viral Diseases · Epidemiology · Immunology · Internal Medicine · Pediatrics

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