Mesenchymal Stem Cell Therapy for Hutchinson–Gilford Progeria
Improvements in Arterial Stiffness and Bone Mineral Density in a Single Case
Bibliographic Data
| ID | 15717682 |
|---|---|
| Authors | Eunyoung Joo (0009-0002-5972-6191, Inha University, corresponding author), Jisun Park (0000-0002-7740-2046), Ji-Sun Park (0000-0003-3793-6577, Inha University), Hyun‐Tae Shin (0000-0003-1799-5860, Inha University), Myungji Yoo (Inha University Hospital), Su Jin Kim (0009-0000-2343-2242, Inha University), Su-Jin Kim (0000-0003-2752-750X, Department of Pediatrics, Inha University College of Medicine, Incheon 22212, Republic of Korea), Ji Eun Lee (0000-0002-4442-4441, Inha University Hospital), Ji-Eun Lee (0000-0002-9565-2508, Department of Pediatrics, Inha University College of Medicine, Incheon 22212, Republic of Korea), Gwang Seong Choi (0000-0002-5766-0179, Inha University Hospital) |
| Year | 2025 |
| Volume | 12 |
| Issue | 4 |
| Pages | 523-523 |
| Publication date | 2025-04-17 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Children (JOURNAL) |
| Journal identifiers | ISSN: 2227-9067 • E-ISSN: 2227-9067 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/children12040523 |
| PMID | 40310235 |
| OpenAlex | W4409588501 |
| Language | EN |
| References cited | 43 |
MSC therapy may offer short-term benefits in arterial stiffness, bone health and inflammation in HGPS without notable safety concerns. Further studies are warranted to validate these findings, explore earlier intervention, and determine long-term efficacy and optimal dosing strategies
Bone mineral · Composite material · Mesenchymal stem cell · Osteoporosis · Pathology · Progeria · Stiffness · Cell death mechanisms and regulation · Chemistry · Materials Science · Medicine · Nuclear Structure and Function · RNA Research and Splicing
| Citation velocity | historical |
|---|---|
| Highly cited | No |