Burden of RSV-Associated Inpatient Care and Emergency Service Utilization in Two German Pediatric Centers Across Six Seasons Including the First Nirsevimab Year
Bibliographic Data
Background/Objectives: Respiratory syncytial virus (RSV) is a major cause of infant respiratory morbidity, yet real-world data on healthcare utilization following universal immunoprophylaxis remain limited. Methods: We retrospectively analyzed RSV-positive inpatient and emergency department (ED) encounters from two German tertiary pediatric centers across six seasons (2019/20-2024/25). Augsburg contributed inpatient data for 2022/23-2024/25, including immunization status and severity metrics, while Erlangen provided inpatient and ED data across all seasons. Results: In Augsburg, RSV hospitalizations were higher in pre-immunization seasons than in 2024/25, accompanied by a reduced proportion of infants Conclusions: Integrated multicenter data descriptively coincide with reduced RSV hospitalization burden following immunoprophylaxis introduction, without evidence of increased disease severity
Coronavirus disease 2019 (COVID-19 · Disease · Emergency department · German · Health care · Immunization · Incidence (geometry · Inpatient care · Pandemic · COVID-19 Clinical Research Studies · Immunodeficiency and Autoimmune Disorders · Respiratory viral infections research
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