Research-Based Intervention (RBI) for Autism Spectrum Disorder
Looking beyond Traditional Models and Outcome Measures for Clinical Trials
Bibliographic Data
| ID | 15719306 |
|---|---|
| Authors | Antonio Narzisi (0000-0003-3996-3827, Fondazione Stella Maris, corresponding author), Yurena Alonso-Esteban (0000-0002-6715-4456, Universitat de València), Gabriele Masi (0000-0001-7770-926X, Fondazione Stella Maris), Francisco Alcantud Marín (0000-0001-6022-5437, Universitat de València) |
| Year | 2022 |
| Volume | 9 |
| Issue | 3 |
| Pages | 430-430 |
| Publication date | 2022-03-18 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Children (JOURNAL) |
| Journal identifiers | ISSN: 2227-9067 • E-ISSN: 2227-9067 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/children9030430 |
| OpenAlex | W4220896671 |
| Language | EN |
| Citations received | 2 |
| References cited | 52 |
The rising prevalence of Autism Spectrum Disorders (ASD) has led to a quickly increasing need for effective interventions. Several criteria and measures have been developed to critically assess these interventions with particular focus on the evaluation of the efficacy. Given the huge diversity of ASD symptoms and the different levels of severity across individuals, identifying a one size fits all intervention approach is challenging, and the question What works and for whom? Remains still unanswered. Why do we seem to be dragging our feet on this fundamental issue? The main aim of this paper is to answer this question through four non-alternative points. First, there are a scarce number of studies with a solid methodology. Secondly, most trials on intervention efficacy for ASD are designed exclusively in terms of behavioral outcomes. Thirdly, there is a reduced use of biologically oriented outcome measures. Fourthly, in most clinical trials, appropriate practices emerging from research evidence are not systematically applied. A strong effort to improve the methodology of clinical trials is mandatory for the future of autism research. The development of a research-based intervention (RBI) perspective aimed at better integrating: (a) evidence-based approaches; (b) more sensitive behavioral outcome measures; and (c) biomarkers, with the aim of increasing a more detailed clustering of phenotypes, may strongly improve our approach to a precision medicine
Autism · Autism spectrum disorder · Clinical trial · Intervention (counseling · Outcome (game theory · Perspective (graphical · Psychiatry · Psychological intervention · Attention Deficit Hyperactivity Disorder · Autism Spectrum Disorder Research · Child Development and Digital Technology · Clinical Psychology · Computer Science · Medicine · Psychology · Artificial Intelligence
The Lancet Commission on the future of care and clinical research in autism
Naturalistic Developmental Behavioral Interventions
Prevalence and Characteristics of Autism Spectrum Disorder Among Children Aged 8 Years — Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2018
Implementation of Video Feedback Within a Community Based Naturalistic Developmental Behavioral Intervention Program for Toddlers With ASD
| Unique citing works | 2 |
|---|---|
| Citations per year | 0,5 |
| Citation span | 2022 - 2025 (4) |
| Citation velocity | recent |
| Highly cited | No |
| Citation types | Neutral: 2 |