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Pediatric Shock Across Acute Emergencies

Age Patterns, Etiologic Subtypes, and Bedside Clinical Indicators in a Single-Centre Cohort

Bibliographic Data

ID15719933
AuthorsCristina Elena Singer (0009-0003-6414-832X, University of Medicine and Pharmacy of Craiova, corresponding author), Ion Dorin Pluta (Constantin Brâncuși University of Targu Jiu), Ştefăniţa Bianca Vintilescu (0000-0002-7801-5646, University of Medicine and Pharmacy of Craiova), Popescu Elena Madalina (University of Medicine and Pharmacy of Craiova), George Alin Stoica (University of Medicine and Pharmacy of Craiova), Renata Maria Văruț (University of Medicine and Pharmacy of Craiova), Renata-Maria Văruț (0000-0002-2845-8609, University of Medicine and Pharmacy of Craiova), Pirscoveanu Denisa Floriana Vasilica (University of Medicine and Pharmacy of Craiova), Virginia Maria Rădulescu (0000-0001-9028-7583, University of Medicine and Pharmacy of Craiova), Nuica Valentina Geanina (Ospedale Valduce), Denisa Preoteasa (Ospedale Valduce), Andreea Gabriela Mocanu (0000-0002-9356-6593, University of Medicine and Pharmacy of Craiova), Carmen Sirbulet (University of Medicine and Pharmacy of Craiova)
Year2026
Volume13
Issue3
Pages366-366
Publication date2026-03-04
Open AccessYes
TypeARTICLE
VenueChildren (JOURNAL)
Journal identifiersISSN: 2227-9067 • E-ISSN: 2227-9067
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/children13030366
PMID41897079
OpenAlexW7133553849
LanguageEN
References cited23

Background/Objectives: Pediatric shock is a final common pathway of cardiovascular failure across diverse emergencies, yet data from mixed emergency cohorts outside intensive care units remain limited. This study aimed to describe the distribution, etiologic subtypes, and clinical correlates of shock in children presenting within a diagnosis-based emergency cohort. Methods : A retrospective single-centre study was conducted in children aged 0-16 years presenting with selected acute pediatric emergencies, among whom cases with and without shock were compared. Shock was defined using documented diagnoses and compatible hemodynamic features, and multiple etiologic types of shock were analyzed, including hypovolemic, septic, cardiogenic, and anaphylactic shock. Demographic and diagnostic variables-age, length of stay, organ support, age strata, and selected comorbidities-and baseline clinical features were compared between children with and without shock using non-parametric and χ 2 /Fisher's exact tests. Results : Within the prespecified diagnosis-based analytic cohort, 36/128 children (28.1%) met the study criteria for shock and occurred across all prespecified acute pediatric emergency groups, with the highest proportional burden in heart failure and meningitis; this proportion should not be interpreted as an emergency-department prevalence estimate. Children with shock were younger, with clustering in infants Conclusions : In this pediatric emergency cohort, shock emerged as a clinically relevant and etiologically heterogeneous complication across diverse acute presentations, with a distinct age-related vulnerability pattern and consistent associations with readily identifiable bedside clinical features. Simple bedside information-particularly cardiac comorbidity, dehydration, and altered consciousness-may assist the early recognition of children with evolving circulatory failure and support closer monitoring and timely escalation of care. By focusing on a mixed emergency population outside the intensive care unit, this study provides a real-world clinical perspective that may help refine early bedside assessment and improve vigilance for shock in pediatric emergency departments

Cardiogenic shock · Cohort · Cohort study · Emergency department · Intensive care · Retrospective cohort study · Sepsis · Septic shock · Shock (circulatory · Cardiac Arrest and Resuscitation · Clinical Reasoning and Diagnostic Skills · Sepsis Diagnosis and Treatment

  • Global, regional, and national sepsis incidence and mortality, 1990–2017

    Open Access•Kristina E Rudd, Sarah C Johnson et al.•The Lancet•2020

Highly citedNo

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