Developmental, behavioural and biochemical markers of anthracene and Pb +2 exposure to zebrafish eleutheroembryos
Bibliographic Data
| ID | 19269324 |
|---|---|
| Authors | Abdelfettah Gherib (0000-0002-7354-8873, Laboratory of Ecotoxicology and Environmental Biomonitoring, Biotechnology Research Centre (CRBt), Constantine, Algeria, corresponding author), Inês Domingues (0009-0000-7436-8420, Department of Biology & Centro de Estudos do Ambiente e do Mar (CESAM), University of Aveiro, Campus Universitário de Santiago, Aveiro, Portugal) |
| Year | 2023 |
| Volume | 80 |
| Issue | 3 |
| Pages | 699-715 |
| Publication date | 2023-05-04 |
| Open Access | No |
| Type | ARTICLE |
| Venue | International Journal of Environmental Studies (JOURNAL) |
| Journal identifiers | ISSN: 0020-7233 • E-ISSN: 1026-7476 |
| Publisher | Informa UK Limited (PUBLISHER • GB) |
| DOI | 10.1080/00207233.2022.2096961 |
| OpenAlex | W4285491289 |
| Language | EN |
| References cited | 39 |
This study aims to assess the toxicity of lead Pb+2 and anthracene in zebrafish (Danio rerio) eleutheroembryos survival, development, behaviour and neurotoxicity. Fish-embryo toxicity (FET) tests were conducted according to the OECD guideline TG 236. The video tracking system Zebrabox® was used to evaluate the effects of these chemicals on 120 hours post fecundation (hpf) larvae behaviour. Data showed that both chemicals have a moderate toxic effect on fish embryo survival: Pb+2 96 h-LC50 value was 76.51 mg/L. Anthracene 96 h-LC50 value was 133.35 mg/L. Anthracene decreased total swimming distance (TSD) and total swimming time (TST) suggesting hypoactivity. Although less pronounced, Pb+2 also affected locomotion by increasing distance travelled in rapid movements after 120 hpf exposure, suggesting hyperactivity. Besides, AChE was not responsive and sensitive to Pb+2 or anthracene after 120 hpf exposure
Andrology · Anthracene · Biology · Danio · Embryo · Fish · Fish <Actinopterygii> · Fishery · Hypoactivity · Neurotoxicity · Toxicity · Zebrafish · Biochemistry · Chemistry · Endocrinology · Environmental Chemistry · Environmental Toxicology and Ecotoxicology · Fish Ecology and Management Studies · Heavy Metal Exposure and Toxicity · Medicine · Toxicology
| Highly cited | No |
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