Fatigue in HIV Illness
Relationship to Depression, Physical Limitations, and Disability
Bibliographic Data
| ID | 19301293 |
|---|---|
| Authors | Stephen J Ferrando (0000-0001-6477-7546, Cornell University), Stephen Ferrando, Susan Evans (0000-0003-0347-604X, Cornell University), Kathy Goggin (0000-0002-8679-9911, Cornell University), Margaret Sewell (Cornell University), Baruch Fishman (Cornell University), Judith G Rabkin (Cornell University), Judith Rabkin |
| Year | 1998 |
| Volume | 60 |
| Issue | 6 |
| Pages | 759-764 |
| Publication date | 1998-01-01 |
| Open Access | No |
| Type | ARTICLE |
| Venue | Psychosomatic Medicine (JOURNAL) |
| Journal identifiers | ISSN: 0033-3174 • E-ISSN: 1534-7796 |
| Publisher | Ovid Technologies (Wolters Kluwer Health) (PUBLISHER) |
| DOI | 10.1097/00006842-199811000-00019 |
| PMID | 9847037 |
| OpenAlex | W1989063363 |
| Language | EN |
| Citations received | 8 |
| References cited | 22 |
OBJECTIVE: This study was conducted to investigate the prevalence of clinical fatigue reported by gay/bisexual men at all HIV illness stages, and whether fatigue, while associated with depression, independently contributes to limitations in physical function and disability. METHOD: HIV- men, HIV+ men with CD4 counts >500, HIV+ men with CD4 counts 200 to 500, and men with AIDS were compared on prevalence of clinical fatigue, as defined by a standardized instrument. Among HIV+ men, the relationships among fatigue, depressed mood, major depressive disorder, HIV illness markers (including CD4 count and HIV RNA viral load), physical limitations, and disability were assessed at baseline and after 1 year. RESULTS: The prevalence of clinical fatigue in men with CD4 counts 500. However, fatigue was not directly correlated with CD4 count or HIV RNA. Fatigue was a chronic symptom that was associated with depressed mood, major depressive disorder, physical limitations, and disability. After 1 year, an increase in depressive symptoms predicted a small amount of variance in fatigue; however, depressive symptoms were not associated with physical limitations or disability after controlling for fatigue. CONCLUSION: Fatigue is a chronic symptom that is more prevalent in advanced HIV illness, and which, although associated with depression, does not seem to be merely a symptom of depression. Because fatigue contributes independently to physical limitations and disability, it should be assessed and treated
Human immunodeficiency virus (HIV) · Psychiatry · Clinical Psychology · Fibromyalgia and Chronic Fatigue Syndrome Research · HIV-related health complications and treatments · HIV/AIDS Research and Interventions · Medicine · Psychology · Virology
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| Citations per year | 0.36 |
|---|---|
| Citation span | 2004 - 2019 (16) |
| Highly cited | No |