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Electrolytes and Osmolality in Alcoholics During Experimentally Induced Intoxication

Bibliographic Data

ID19301548
AuthorsMOTOI OGATA (National Institute of Mental Health), Jack H Mendelson (National Institute of Mental Health), Nancy K Mello (National Institute of Mental Health)
Year1968
Volume30
Issue5
Pages463-488
Publication date1968-09-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenuePsychosomatic Medicine (JOURNAL)
Journal identifiersISSN: 0033-3174 • E-ISSN: 1534-7796
PublisherOvid Technologies (Wolters Kluwer Health) (PUBLISHER)
DOI10.1097/00006842-196809000-00001
PMID5725376
OpenAlexW2318333038
LanguageEN
Citations received1
References cited5

Serum and urine osmolality and electrolytes were measured in 6 alcoholic subjects prior to, during, and following a period of experimentally induced ethanol intoxication. A significant increase in serum osmolality was correlated with increased levels of serum sodium. Diuresis only occurred during the initial phase of alcohol administration and did not persist during prolonged drinking. Hematocrit levels decreased although dietary and vitamin intake was adequate. A significant decrease in urine electrolyte excretion occurred during the alcohol ingestion phase even though urine volume output did not differ from prealcohol values. It is postulated that chronic ethanol intake is associated with electrolyte derangements which cannot be explained by known diuretic or hormonal changes induced by ethanol ingestion

Alcohol · Alcohol intoxication · Antidiuretic · Diuresis · Diuretic · Electrolyte · Ethanol · Excretion · Hematocrit · Hormone · Ingestion · Kidney · Osmoreceptor · Plasma osmolality · Poison control · Sodium · Thirst · Urine · Urine osmolality · Vasopressin · Alcohol Consumption and Health Effects · Alcoholism and Thiamine Deficiency · Biochemistry · Chemistry · Endocrinology · Internal Medicine · Medicine · Pharmacology and Obesity Treatment

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Unique citing works1
Citations per year0,03
Citation span1988 - 1988 (1)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 1

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